UTP3 Protein (AA 1-469) (His tag)

Catalog No. ABIN7561528

Product Details

Target: UTP3 (UTP3, Small Subunit (SSU) Processome Component (UTP3))

Protein Type: Recombinant

Protein Characteristics: AA 1-469

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This UTP3 protein is labelled with His tag.

Purpose: Custom-made recombinant Utp3 Protein expressed in mammalian cells.

Sequence: MVKKSRRRGA AQWAAVRAQA GLTATDENED DLGLPPSPGD SSYYQDQVDE FHEARSRAVL AKGWNEVESG EEDGDEEEEV LPLDIDDGDD EDGESSEEEE VGEDDDGGSS VQSEAEASVD PSLSWGQRKK LYYDTDYGSK SRGRQSQQEV EEEEREEEEE AQIIQRRLAQ ALQEDDFGVA WVEAFAKPVP QVDEAETRVV KDLAKVSVKE KLKMLKKESP ELLELIEDLQ AKLTEVKDEL EPLLQLVEKG VIPTGRGSEY LKTKYNLYLN YCANISFYLI LKARRVPAHG HPVIERLVTY RNLINKLSVV DQKLSSEIRH LLTAKDGAVK KEMTPKAKLT KTKPKSVKQA AAVALTDEPD FDGAALKYYK EMEDRQELKR KKEENSAEEQ ALEEQNAKRA ITYQIAKNRG LTPRRKKIDR NPRVKHREKF RKAKIRRRGQ VREVRREEQR YSGELSGIRA GVKKSIKLK Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: UTP3 (UTP3, Small Subunit (SSU) Processome Component (UTP3))

Alternative Name: Utp3 (UTP3 Products)

Background: Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (Crl-1) (Disrupter of silencing SAS10) (UTP3 homolog),FUNCTION: Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity). {ECO:0000250|UniProtKB:Q12136, ECO:0000250|UniProtKB:Q9NQZ2, ECO:0000269|PubMed:11404095}.

Molecular Weight: 53.4 kDa

UniProt: Q9JI13

AlphaFold: Q9JI13