SERTAD2 Protein (AA 1-309) (His tag)
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- Target See all SERTAD2 Proteins
- SERTAD2 (SERTA Domain Containing 2 (SERTAD2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-309
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SERTAD2 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Sertad2 Protein expressed in mammalian cells.
- Sequence
- MLGKGGKRKF DEHEDGLEGK IVSPSDGPSR VSYTLQRQTI FNISLMKLYN HRPLTEPSLQ KTVLINNMLR RIQEELKQEG SLRPAFTPSS QPSNSLSDSY QEAPPPAPHP CDLGSTTPLE ACLTPASLLE DDNDDTFCTL QAVHPAAPTR LSSAALPAEK DSFSSALDEI EELCPTSTST EAAHTAAPEG PKGTSSESSV QKPEGPEEGR TDDSRFMDSL PGNFEITTST GFLTDLTLDD ILFADIDTSM YDFDPCTSAS GTASKMAPVS ADDLLKTLAP YSNQPVAPSQ PFKMDLTELD HIMEVLVGS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product SERTAD2 Protein
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SERTA Domain Containing 2 (SERTAD2) (AA 1-314) protein (His tag)
custom-made SERTAD2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
SERTA Domain Containing 2 (SERTAD2) (AA 1-314) protein (His tag)SERTAD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
SERTA Domain Containing 2 (SERTAD2) (AA 1-314) protein (GST tag)SERTAD2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- SERTAD2 (SERTA Domain Containing 2 (SERTAD2))
- Alternative Name
- Sertad2 (SERTAD2 Products)
- Background
- SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2),FUNCTION: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism. {ECO:0000269|PubMed:23291629}.
- Molecular Weight
- 33.3 kDa
- UniProt
- Q9JJG5
- AlphaFold
- Q9JJG5
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