Slc6a14 Protein (AA 1-638) (His tag)

Catalog No. ABIN7561700

Product Details

Target: Slc6a14 (Solute Carrier Family 6 (Amino Acid Transporter), Member 14 (Slc6a14))

Protein Type: Recombinant

Protein Characteristics: AA 1-638

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This Slc6a14 protein is labelled with His tag.

Purpose: Made-to-order recombinant Slc6a14 Protein expressed in mammalian cells.

Sequence: MDRLKCPNFF KCRQKEKVTA SSENFHVGEN DENQERGNWS KKSDYLLSMV GYAVGLGNVW RFPYLTYTNG GGAFLIPYAI MLALAGLPLF FLECSLGQFA SLGPVSVWRI LPLFQGVGIT MVLISVFVAI YYNVIIAYSL YYLFASFQSV LPWANCSSWA DENCSRTPIV TGCNVSIGAG EMFMNISWVN TNNLTCLNGS EVFRPGQLPS EQYWDKVTLQ RSSGMDETGV VVWYLALCLL LAWLIVGAAL FKGIKSSGKV VYFTALFPYV VLLILLIRGA TLEGASKGIS YYIGAQSNFT KLREAEVWKD AATQIFYSLS VAWGGLVALS SYNKFNNNCY SDAIIVCLTN CLTSVFAGFA IFSILGHMAH ISGKEVSQVV KSGFDLAFIA YPEALAQLPA GPFWSILFFF MLLTLGLDSQ FASIETITTT FQDLFPKAMK RMRVPITLGC CLILFLLGLL CVTQAGIYWV HLIDHFCAGW GILIAAILEI AGIIWIYGGN RFIEDIEMMI GAKRWIFWLW WRACWFVITP ILLSAILVWS LVKFHRPDYA DIPYPDWGVA LGWCMIIFCI IWIPIMAIIK IVQAEGNILQ RIISCCRPAS NWGPYLEKHR GERYRDMAEP AKETDHEIPT ISGSTKPE Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: Slc6a14 (Solute Carrier Family 6 (Amino Acid Transporter), Member 14 (Slc6a14))

Alternative Name: Slc6a14 (Slc6a14 Products)

Background: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Colonic system B0+ amino acid transporter CATB0+) (Solute carrier family 6 member 14),FUNCTION: Amino acid transporter that plays an important role in the absorption of amino acids in the intestinal tract. Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner (PubMed:11306607, PubMed:11447016). Transports non-alpha-amino acids such as beta-alanine with low affinity, and has a higher affinity for dipolar and cationic amino acids such as leucine and lysine (By similarity). Can also transport carnitine, butyrylcarnitine and propionylcarnitine coupled to the transmembrane gradients of Na(+) and Cl(-) (PubMed:11306651). {ECO:0000250|UniProtKB:Q9UN76, ECO:0000269|PubMed:11306607, ECO:0000269|PubMed:11306651, ECO:0000269|PubMed:11447016}.

Molecular Weight: 71.5 kDa

UniProt: Q9JMA9

AlphaFold: Q9JMA9