PTCHD2 Protein (AA 1-1347) (His tag)
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- Target See all PTCHD2 Proteins
- PTCHD2 (Patched Domain Containing 2 (PTCHD2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-1347
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTCHD2 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Disp3 Protein expressed in mammalian cells.
- Sequence
- MDSEDDPLLQ DVWLEEEQPE DEACRGIPGP GLQSGAQGCW RRWTLPSRPP TLGFWSTLGW AFTNPCCAGL VLFLGCSIPM VLSAFMFLYY PPLDIDISYN AFEIRNHEAS QRFDALALAL KSQFGSWGRN RRDLADFTSE TLQRLISEQL QQLHLGNHSR PASRAPRSAP RDTVATQTSA ANSSERRRRE APSPEGQVTN QSRARRGASR WDYSRTYVSA NTQTHAHWRI ELIFLARGDA ERNIFTSERL VTIHEIERKI MDHPGFREFC WKPHEVLKDL PLGSYSYCSP PSSLMTYFFP TERGGKIYYD GMGQDLADIR GSLELAMTHP EFYWYVDEGL SVDNLKSSLL RSEILFGAPL PNYYSVDDRW EEQRAKFQSF VVTYVAMLAK QSTSKVQVLY GGTDLFDYEV RRTFNNDMLL AFISSSCIAA LVYILTSCSV FLSFFGIASI GLSCLVALFL YHVVFGIQYL GILNGVAAFV IVGIGVDDVF VFINTYRQAT HLEDPQLRMI HTIQTAGKAT FFTSLTTAAA YAANVFSQIP AVHDFGLFMS LIVTCCWLAV LFTMPAALGL WSLYMAPLES SCQNSCHQKC GRKSSLHFPG DLFTAPERAG GGPAQGPLPY LDDDIPLLNV EDEPASLELG DVSLVSVHCE GLQPTPDANS RGQLLAQLQE LLHHWVLWAA VKSRWVIVGL FASILILSLV FASRLRPASR APLLFRPDTN IQVLLDLKYN LSAEGISCIT CSGLFQEKPH SLQNNVRTSL EKKKRGSGVS WASRTETTAQ ESMSTVYISK VKSKGHPAVY RLSLNASLPA PWQAVSPGDG EVPSFQVYRA PFGDFTKKLT ACMSTVGLLQ AASPSRKWMV TALACDARRG WKFDFSFYVA TKEQQHTRKL YFAQSHKPPF HGRLCVAPPG CLLSSSPDGP TKGFFYVPSD KVPKARISAT FGFNPCVNTG CGKPAVRPLV DTGAMVFVVF GIIGLNRTQQ MDNHVIGDPG SVIYDSSFDL FKEIGHLCRL CKAIAGNSEL VKPGGAQCLP SGYSISSFLQ MLHPECKELP EPNLLPGQLS HGAVGVKEGR VQWISMAFES TTYKGKSSFQ TYSDYLRWES FLRQQLQTFP EGSALHRGFQ TCEHWKQIFM EIIGVQSALY GLVLSLLICV AAVAVFTTHV LLLLPVLLSI LGIVCLVVTI MYWSGWEMGA VEAISLSILV GSSVDYCVHL VEGYLLAGEN LPPQLSQDPS SQRQWRTLEA VRHVGVAIVS SALTTVIATV PLFFCIIAPF AKFGKIVALN TGVSILYTLT VSTALLGIMA PGSFTRTRTS FLKALGAVLL AGALGLGACL VLLRSGYKIP LPSGATL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product PTCHD2 Protein
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- PTCHD2 (Patched Domain Containing 2 (PTCHD2))
- Alternative Name
- Disp3 (PTCHD2 Products)
- Background
- Protein dispatched homolog 3 (Patched domain-containing protein 2) (RND-type protein RNDEu-2),FUNCTION: Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol. Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells. {ECO:0000250|UniProtKB:B9U3F2, ECO:0000250|UniProtKB:Q9P2K9}.
- Molecular Weight
- 148.4 kDa
- UniProt
- A3KFU9
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