RRN3 Protein (AA 1-656) (His tag)
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- Target See all RRN3 Proteins
- RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-656
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RRN3 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Rrn3 Protein expressed in mammalian cells.
- Sequence
- MAAPLLHTRL SGDVTAAASA TLSASRTGLS DMLALESDFF NSPPKKTVRF GGTVTEVLLK YKKGETNDLE LLKNQLSDPD IKDDQIINWL LEFRSSVMYL TKDFEQLINI ILRLPWLNRS QRVVEEYLAF LGNLVSAQTV FLRPCLSMIA SHFVPPRVIV KEGGIDVSDS DDEDDNLPAI FDTCHRALQI ITRYVPSTPW FLMPILVEKF PFVRKSERTL ECYVHNLLRI SLYFPTLRRE ILELVIEKLL KLDVSVSRQD IEDAEEKAAQ TCGGTDTTEG LFNMDEDEDT DPEKKADQEQ PNQMAHPTAE RLDVLLCLLL SYIEDVCRVH GKIDNNKTKD LYRDLISIFD KLLLPTHASC HVQFFMFFLC SFKLGFAEAF LEHLWKKLQD PNNPAIIRQA AANYIGSFLA RAKFIPLITV KTCLDLLVNW LHMYLTNQDS GTKAFCDVAL HGPFYSACQA VFYTVVFRHK QLLSGNLKQG LQYLQSLNFE RIVLSQLNPL KICLPQVVNF FAAITNKYQL VFCYTIMERN SRQMLPVIRS TAGGDSVQTC TNPLDTFFPF DPCVLKRSKK FIDPIYQIWE DGSAEELQEF KKSTKKEVVE DEDDDFLKGE VPQSDTVTGL TPSSFDTHFQ SPSSSVGSPP VLYIPGQSPL LTRIYD Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))
- Alternative Name
- Rrn3 (RRN3 Products)
- Background
- RNA polymerase I-specific transcription initiation factor RRN3,FUNCTION: Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent pre-initiation complex (PIC). {ECO:0000269|PubMed:12015311, ECO:0000269|PubMed:12646563}.
- Molecular Weight
- 74.5 kDa
- UniProt
- B2RS91
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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