ST14 Protein (AA 1-855) (His tag)

Catalog No. ABIN7563458

Product Details

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Protein Type: Recombinant

Protein Characteristics: AA 1-855

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This ST14 protein is labelled with His tag.

Purpose: Made-to-order recombinant St14 Protein expressed in mammalian cells.

Sequence: MGSNRGRKAG GGSQDFGAGL KYNSRLENMN GFEEGVEFLP ANNAKKVEKR GPRRWVVLVA VLFSFLLLSL MAGLLVWHFH YRNVRVQKVF NGHLRITNEI FLDAYENSTS TEFISLASQV KEALKLLYNE VPVLGPYHKK SAVTAFSEGS VIAYYWSEFS IPPHLAEEVD RAMAVERVVT LPPRARALKS FVLTSVVAFP IDPRMLQRTQ DNSCSFALHA HGAAVTRFTT PGFPNSPYPA HARCQWVLRG DADSVLSLTF RSFDVAPCDE HGSDLVTVYD SLSPMEPHAV VRLCGTFSPS YNLTFLSSQN VFLVTLITNT DRRHPGFEAT FFQLPKMSSC GGFLSDTQGT FSSPYYPGHY PPNINCTWNI KVPNNRNVKV RFKLFYLVDP NVPVGSCTKD YVEINGEKYC GERSQFVVSS NSSKITVHFH SDHSYTDTGF LAEYLSYDSN DPCPGMFMCK TGRCIRKELR CDGWADCPDY SDERYCRCNA THQFTCKNQF CKPLFWVCDS VNDCGDGSDE EGCSCPAGSF KCSNGKCLPQ SQKCNGKDNC GDGSDEASCD SVNVVSCTKY TYRCQNGLCL SKGNPECDGK TDCSDGSDEK NCDCGLRSFT KQARVVGGTN ADEGEWPWQV SLHALGQGHL CGASLISPDW LVSAAHCFQD DKNFKYSDYT MWTAFLGLLD QSKRSASGVQ ELKLKRIITH PSFNDFTFDY DIALLELEKS VEYSTVVRPI CLPDATHVFP AGKAIWVTGW GHTKEGGTGA LILQKGEIRV INQTTCEDLM PQQITPRMMC VGFLSGGVDS CQGDSGGPLS SAEKDGRMFQ AGVVSWGEGC AQRNKPGVYT RLPVVRDWIK EHTGV Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Alternative Name: St14 (ST14 Products)

Background: Suppressor of tumorigenicity 14 protein homolog (EC 3.4.21.109) (Epithin) (Serine protease 14),FUNCTION: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site (By similarity). Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing (By similarity). Proteolytically cleaves and therefore activates TMPRSS13 (By similarity). {ECO:0000250|UniProtKB:Q9Y5Y6}.

Molecular Weight: 94.7 kDa

UniProt: P56677

AlphaFold: P56677