TTBK1 Protein (AA 1-1308) (His tag)

Catalog No. ABIN7564112

Product Details

Target: TTBK1 (Ttbk1) (tau Tubulin Kinase 1 (Ttbk1))

Protein Type: Recombinant

Protein Characteristics: AA 1-1308

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This TTBK1 protein is labelled with His tag.

Purpose: Custom-made recombinant Ttbk1 Protein expressed in mammalian cells.

Sequence: MQCLAAALKD ETNMSGGGEQ ADILPANYVV KDRWKVLKKI GGGGFGEIYE AMDLLTRENV ALKVESAQQP KQVLKMEVAV LKKLQGKDHV CRFIGCGRNE KFNYVVMQLQ GRNLADLRRS QPRGTFTLST TLRLGKQILE SIEAIHSVGF LHRDIKPSNF AMGRLPSTYR KCYMLDFGLA RQYTNTTGDV RPPRNVAGFR GTVRYASVNA HKNREMGRHD DLWSLFYMLV EFAVGQLPWR KIKDKEQVGM IKEKYEHRML LKHMPSEFHL FLDHIASLDY FTKPDYQLIM SVFENSMKER GIAENEAFDW EKAGTDALLS TSTSTPPQQN TRQTAAMFGV VNVTPVPGDL LRENTEDVLQ GEHLSDQENA PPILPGRPPE GLGPGPHLVP HPGGPEAEVW EETDVNRNKL RINIGKTPCV EEEQSRGVGV PSSPVRAPPD SPTTPVRSLC YRRVNSPESE RLSTAADGRV ELQERRSRMD LPGSPSRQAC SSQPAQMLSV DTGHADRQAS GRMDVSASVE QEALSNAFRS VPLAEEEDFD SKEWVIIDKE TELKDFPPGA EPSTSGTTDE EPEELRPLPE EGEERRRLGT EPTVRPRGRG MHTLTEEDPR QMLPQPAPPQ LSQADGRSET SQPPTPGSPS HSPLHSGPRP RRRESDPTGP QRQVFSVAPP FEVNGLPRAV PLALPYQDFK RDLSDYRERA RLLNRVRRVG FSHMLLTAPQ VPLAPFQPQA NGKEGEEEEE EEEEEEEEEE EEEEEEEEEE EEEEEEEEAG ALGEVLGPRS GSSSEGSERS TERSQEGAPS TLLADDQKEA RGRASMADGD LEPEEGSKTL VLVSPGDMKK SPVTAELAPD PDLGTLAALT PQHERPQPTG SQLDVSEPGT LSSILKSEPK PSGPGAGGGV GLVAPGAGVT AVTSPFTKVE RTFVHIAEKS HLNVMSSGGQ ASRPEELSTG GELGLEVLSE GGIAEEGAPA PLENGMALAG LDGTEMESCA LSGPPGETPS EVVTDSLPNG PALADGPAPA SQQEPVTKKG TTISPSRHAM PGSRPRSRIP VLLSEEDTGS EPSGSLSAKE RWSKRARPQQ DLARLVMEKR QGRLLLRLAS GASSSSSEEQ RRASETLSGT GSEEDTPASE PTTALPRKAV RAATTRSRIP RPISVSMPVE GQQLPGRPHG AASATDLAIT SRLQLQKPSG LAPAADLRPK QSASRGPGPG RAQVSKPAAP RSPGLPASTA RHPSGSPRSQ SLSRKESSSP SHQARPGVPP SRGVLQVRSQ PEASPVAPKK GPKGKQLQTQ RAATKGRAVV SEGRPGAR Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TTBK1 (Ttbk1) (tau Tubulin Kinase 1 (Ttbk1))

Alternative Name: Ttbk1 (Ttbk1 Products)

Background: Tau-tubulin kinase 1 (EC 2.7.11.1),FUNCTION: Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU (By similarity). {ECO:0000250}.

Molecular Weight: 141.6 kDa

UniProt: Q6PCN3