SLC25A24 Protein (AA 1-475) (His tag)

Catalog No. ABIN7564394

Product Details

Target: SLC25A24 (Solute Carrier Family 25 (Mitochondrial Carrier, Phosphate Carrier), Member 24 (SLC25A24))

Protein Type: Recombinant

Protein Characteristics: AA 1-475

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This SLC25A24 protein is labelled with His tag.

Purpose: Custom-made recombinant Slc25a24 Protein expressed in mammalian cells.

Sequence: MLRWLRAFVL PTAACHDAEP PTRYETLFRA LDRNGDGVVD IGELQQGLQS LGIPLGQDAE EKIFTTGDVN KDGKLDFEEF MKYLKDHEKK MKLAFKSLDK NNDGKIEPSE IVQSLQMLGL HISEKQAELI LQSIDSDGTM TVDWNEWRDY FLFNPVTDIE EIIRFWKHST GIDIGDSLTI PDEFTEDEKK SGQWWRQLLA GGVAGAVSRT STAPLDRLKV MMQVHGSKSM NIFGGFRQMV KEGGIRSLWR GNGTNVIKIA PETAVKFWAY EQYKKLLTEE GQKLGTFERF ISGSMAGATA QTFIYPMEVL KTRLAVAKTG QYSGIYGCAK KILKHEGFGA FYKGYIPNLL GIIPYAGIDL AVYELLKSYW LDNFAKDSVN PGVMVLLSCG ALSSTCGQLA SYPLALVRTR MQAQATVEGA PQLSMVGLFQ RIVSKEGVSG LYRGITPNFM KVLPAVGISY VVYENMKQTL GVAQK Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC25A24 (Solute Carrier Family 25 (Mitochondrial Carrier, Phosphate Carrier), Member 24 (SLC25A24))

Alternative Name: Slc25a24 (SLC25A24 Products)

Background: Mitochondrial adenyl nucleotide antiporter SLC25A24 (Small calcium-binding mitochondrial carrier protein 1) (SCaMC-1) (Solute carrier family 25 member 24),FUNCTION: Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates. {ECO:0000250|UniProtKB:Q6NUK1}.

Molecular Weight: 52.9 kDa

UniProt: Q8BMD8