CATSPER1 Protein (AA 1-686) (His tag)

Catalog No. ABIN7564835

Product Details

Target: CATSPER1 (Cation Channel, Sperm Associated 1 (CATSPER1))

Protein Type: Recombinant

Protein Characteristics: AA 1-686

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This CATSPER1 protein is labelled with His tag.

Purpose: Made-to-order recombinant Catsper1 Protein expressed in mammalian cells.

Sequence: MDQSSRRDES YHETHPGSLD PSHQSHPHPH PHPTLHRPNQ GGVYYDSPQH GMFQQPYQQH GGFHQQNELQ HLREFSDSHD NAFSHHSYQQ DRAGVSTLPN NISHAYGGSH PLAESQHSGG PQSGPRIDPN HHPHQDDPHR PSEPLSHPSS TGSHQGTTHQ QYHERSHHLN PQQNRDHADT ISYRSSTRFY RSHAPFSRQE RPHLHADHHH EGHHAHSHHG EHPHHKEQRH YHGDHMHHHI HHRSPSASQL SHKSHSTLAT SPSHVGSKST ASGARYTFGA RSQIFGKAQS RESLRESASL SEGEDHVQKR KKAQRAHKKA HTGNIFQLLW EKISHLLLGL QQMILSLTQS LGFETFIFIV VCLNTVILVA QTFTELEIRG EWYFMVLDSI FLSIYVLEAV LKLIALGLEY FYDPWNNLDF FIMVMAVLDF VLLQINSLSY SFYNHSLFRI LKVFKSMRAL RAIRVLRRLS ILTSLHEVAG TLSGSLPSIT AILTLMFTCL FLFSVVLRAL FQDSDPKRFQ NIFTTLFTLF TMLTLDDWSL IYIDNRAQGA WYIIPILMIY IVIQYFIFLN LVIAVLVDNF QMALLKGLEK VKLEQAARVH EKLLDDSLTD LNKADANAQM TEEALKMQLI EGMFGNMTVK QRVLHFQFLQ LVAAVEQHQQ KFRSQAYVID ELVDMAFEAG DDDYGK Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: CATSPER1 (Cation Channel, Sperm Associated 1 (CATSPER1))

Alternative Name: Catsper1 (CATSPER1 Products)

Background: Cation channel sperm-associated protein 1 (CatSper1),FUNCTION: Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization. {ECO:0000269|PubMed:11595941, ECO:0000269|PubMed:14657352, ECO:0000269|PubMed:16036917, ECO:0000269|PubMed:16467839, ECO:0000269|PubMed:17174296}.

Molecular Weight: 78.7 kDa

UniProt: Q91ZR5

AlphaFold: Q91ZR5