SERPINA12 Protein (AA 21-413) (DYKDDDDK Tag)
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- Target See all SERPINA12 Proteins
- SERPINA12 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-413
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SERPINA12 protein is labelled with DYKDDDDK Tag.
- Purpose
- Vaspin (mouse) (rec.)
- Cross-Reactivity
- Mouse
- Characteristics
- Mouse vaspin (aa 21-413) is fused at the N-terminus to a DYKDDDDK Tag.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test).
- Top Product
- Discover our top product SERPINA12 Protein
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serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12) (AA 1-414) protein (GST tag)
SERPINA12 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12) (AA 21-414) protein (His tag)SERPINA12 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- 0.1 mg/mL after reconstitution
- Concentration
- 0.1 mg/mL
- Buffer
- Contains PBS.
- Handling Advice
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.For maximum product recovery after thawing, centrifuge the vial before opening the cap.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- Target
- SERPINA12 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12))
- Alternative Name
- Vaspin (SERPINA12 Products)
- Background
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Visceral Adipose Tissue-derived Serine Protease Inhibitor, Serpin A12, Visceral Adipose-specific Serpin
Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Vaspin modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and is correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.
- Molecular Weight
- ~55kDa (SDS-PAGE)
- UniProt
- Q7TMF5
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