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ADD2 Proteins

(Adducin 2 (Beta) (ADD2))

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010].

recommended

ADD2 Protein (AA 1-726) (GST tag) (ABIN1305969)

ADD2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

ADD2 Protein (AA 1-726) (Strep Tag) (ABIN3088423)

Crystallography grade ADD2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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recommended

ADD2 Protein (AA 2-725) (His tag) (ABIN3130516)

Crystallography grade ADD2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys

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ADD2 Proteins by Grade

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ADD2 Proteins by Origin

Find ADD2 Proteins for a variety of species such as anti-Human ADD2, anti-Mouse ADD2, anti-Rat ADD2. The species listed below are among those available. Click on a link to go to the corresponding products.

ADD2 Proteins by Source

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ADD2 Proteins by Protein Type

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ADD2 Proteins by Application

Find ADD2 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ADD2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

ADD2 Protein (AA 1-726) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1305969

Quantity 10 μg

Datasheet Datasheet

ADD2 Protein (AA 1-726) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3088423

Quantity 1 mg

Datasheet Datasheet

ADD2 Protein (AA 2-725) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3130516

Quantity 1 mg

Datasheet Datasheet

ADD2 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2715230

Quantity 20 μg

Datasheet Datasheet

ADD2 Protein (AA 1-725) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1473793

Quantity 1 mg

Datasheet Datasheet

Aliases for ADD2 Proteins

adducin 2 (ADD2) Proteins
adducin 2 (beta) (add2) Proteins
adducin 2 (add2) Proteins
adducin 2 (beta) (Add2) Proteins
adducin 2 (Add2) Proteins
2900072M03Rik Proteins
add97 Proteins
ADDB Proteins
beta-ADD Proteins
si:dkey-202n14.5 Proteins

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ADD2 Proteins by Grade

ADD2 Proteins by Origin

ADD2 Proteins by Source

ADD2 Proteins by Protein Type

ADD2 Proteins by Application

Popular ADD2 Proteins

Aliases for ADD2 Proteins

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