anti-BCL2-Associated Athanogene 4 Antibodies

Protein Summary

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with BCL2-Associated Athanogene 4 (BAG4)

• BCL2 associated athanogene 4 (BAG4) antibody
• BCL2-associated athanogene 4 (Bag4) antibody
• BCL2-associated athanogene 4 (bag4) antibody
• BCL-2-associated athanogene 4 (BAG4) antibody
• BCL2 associated athanogene 4 (Bag4) antibody

• 2410112I15Rik antibody
• ATBAG4 antibody
• BAG-4 antibody
• BAG4 antibody
• BCL-2-associated athanogene 4 antibody
• Show all synonym aliases
• fd20a04 antibody
• si:dkey-220o5.3 antibody
• SODD antibody
• wu:fd20a04 antibody

Protein level used designations for BAG4

BAG family molecular chaperone regulator 4 , BAG-family molecular chaperone regulator-4 , bcl-2-associated athanogene 4 , silencer of death domains , BCL2-associated athanogene 4 , BAG-4