Protein Summary

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Alternative names and synonyms associated with BAI1-Associated Protein 2-Like-1 (BAIAP2L1)

• BAI1-associated protein 2-like 1a (baiap2l1a) antibody
• BAI1 associated protein 2 like 1 (BAIAP2L1) antibody
• BAI1 associated protein 2 like 1 L homeolog (baiap2l1.L) antibody
• BAI1-associated protein 2-like 1 (Baiap2l1) antibody

• 1300006M19Rik antibody
• AI585895 antibody
• BAIAP2L1 antibody
• cb1023 antibody
• IRTKS antibody
• Show all synonym aliases
• MGC131079 antibody
• RGD1308452 antibody
• zgc:85624 antibody

Protein level used designations for BAIAP2L1

BAI1-associated protein 2-like 1 , insulin receptor tyrosine kinase substrate homolog , insulin receptor tyrosine kinase substrate , brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1-like , BAI1-associated protein 2-like protein 1 , brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1