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anti-Mouse (Murine) CXCR4 Antibodies:
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Human Monoclonal CXCR4 Primary Antibody for CyTOF, FACS - ABIN4900744
Griffiths, Dolezal, Cao, Nilsson, See, Pfleger, Roche, Gorry, Pow, Viduka, Lim, Lu, Chang, Murray-Rust, Kvansakul, Perugini, Dogovski, Doerflinger, Zhang, Parisi, Casey, Nuttall, Foley: i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4. in The Journal of biological chemistry 2016
Show all 25 Pubmed References
Human Monoclonal CXCR4 Primary Antibody for CyTOF, FACS - ABIN4900745
Hansson, Olesen, Peterslund, Engberg, Kahn, Winzi, Klein, Maddox-Hyttel, Serup: A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells. in Developmental biology 2009
Show all 21 Pubmed References
Human Monoclonal CXCR4 Primary Antibody for FACS - ABIN4898488
Peled, Abraham, Avivi, Rowe, Beider, Wald, Tiomkin, Ribakovsky, Riback, Ramati, Aviel, Galun, Shaw, Eizenberg, Hardan, Shimoni, Nagler: The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34+ cells in patients with multiple myeloma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014
Show all 17 Pubmed References
Human Monoclonal CXCR4 Primary Antibody for FACS - ABIN4898487
Misao, Takemura, Arai, Ohno, Onogi, Takahashi, Minatoguchi, Fujiwara, Fujiwara: Importance of recruitment of bone marrow-derived CXCR4+ cells in post-infarct cardiac repair mediated by G-CSF. in Cardiovascular research 2006
Show all 17 Pubmed References
Human Polyclonal CXCR4 Primary Antibody for ICC, IF - ABIN261500
Hasegawa, McLeod, Prow, Merges, Grebe, Lutty: Vascular precursors in developing human retina. in Investigative ophthalmology & visual science 2008
Show all 15 Pubmed References
Human Monoclonal CXCR4 Primary Antibody for CyTOF, FACS - ABIN4900746
Albanesi, Scarponi, Pallotta, Daniele, Bosisio, Madonna, Fortugno, Gonzalvo-Feo, Franssen, Parmentier, De Pità, Girolomoni, Sozzani: Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. in The Journal of experimental medicine 2009
Show all 15 Pubmed References
Mouse (Murine) Monoclonal CXCR4 Primary Antibody for CyTOF, FACS - ABIN4899088
Rider, Carmi, Guttman, Braiman, Cohen, Voronov, White, Dinarello, Apte: IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2011
Show all 15 Pubmed References
Human Polyclonal CXCR4 Primary Antibody for ICC, IF - ABIN4301203
Kulbe, Hagemann, Szlosarek, Balkwill, Wilson: The inflammatory cytokine tumor necrosis factor-alpha regulates chemokine receptor expression on ovarian cancer cells. in Cancer research 2005
Show all 13 Pubmed References
Human Polyclonal CXCR4 Primary Antibody for FACS, IF (p) - ABIN730888
Zhuo, Jia, Song, Lu, Ding, Wang, Song, Fu, Luo: The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012
Show all 12 Pubmed References
Human Monoclonal CXCR4 Primary Antibody for FACS - ABIN2689042
Hesselgesser, Halks-Miller, DelVecchio, Peiper, Hoxie, Kolson, Taub, Horuk: CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons. in Current biology : CB 1997
Show all 10 Pubmed References
bilateral lineup in the trunk before PGC migration colonizing gonadal areas is defective in PGCS expressing a missense mutation in chemokine receptor gene cxcr4b
Hyaluronic acid-laminin hydrogels increase neural stem cell transplant retention and migratory response to SDF-1alpha in a manner critically dependent on signaling via the SDF-1alpha-CXCR4 axis.
The Function of SDF-1-CXCR4 Axis in SP Cells-Mediated Protective Role for Renal Ischemia/Reperfusion Injury by SHH/GLI1-ABCG2 Pathway
the pivotal role of CXCR4- and CXCR7 (show CXCR7 Antibodies)-inhibition in acute pulmonary inflammation, which depended on A2B (show ADORA2B Antibodies)-receptor signaling, is reported.
CXCR4 signaling is critical for perivascular invasion of GBM cells and radiation sensitivity.
The results provide the first evidence that upregulation of TGFb (show TGFB1 Antibodies)/Smad3 (show SMAD3 Antibodies) in injured arteries induces local smooth muscle cells CXCR4 expression and cell migration, and consequently intimal hyperplasia.
results characterize CXCR4 as an important pathway that modulates immune dysfunction and mortality following sepsis, which may hold promise as a target for future therapeutic intervention in septic patients
CXCL12 (show CXCL12 Antibodies)/CXCR4 signaling negatively modulates the bipotential state of Hemogenic endothelial cells independently of the hematopoietic fate.
Efficient plasma cell differentiation and trafficking require Cxcr4 desensitization.
High CXCR4 expression is associated with Prostate Cancer.
Data show that FLT3 ligand (FLT3L (show FLT3LG Antibodies)) enhances thymopoiesis through increased survival and export of hematopoietic stem cell (Lin([minus])Sca1 (show ATXN1 Antibodies)(+)c-Kit (show KIT Antibodies)(+) [LSK (show LCK Antibodies)] cells via CXCR4 receptor regulation.
These results showed that targeting CXCR4 by CRISPR/Cas9 could inhibit proliferation, migration and invasion, reversed epithelial-mesenchymal transition , increased chemosensitivity and decrease the malignancy of HCC (show FAM126A Antibodies) in vitro and in vivo.
Results provide evidence that chemokine receptor CXCR4 plays a crucial role in mediating oxidative stress-induced (show SQSTM1 Antibodies) podocyte injury, proteinuria, and renal fibrosis.
findings demonstrate that induction of ibrutinib resistance in WM cells can arise independent of BTK (show BTK Antibodies)(C481S) and CXCR4(WHIM-like) mutations and sustained pressure from ibrutinib appears to activate compensatory AKT (show AKT1 Antibodies) signaling as well as reshuffling of Bcl-2 (show BCL2 Antibodies) family proteins for maintenance of cell survival.
Tetramethylpyrazine-mediated regulation of CXCR4 in retinoblastoma is sensitive to cell density
Co-expression of Lgr5 (show LGR5 Antibodies) and CXCR4 characterizes cancer stem-like cells of colorectal cancer.
We propose that DUX4 controls the cellular migration of mesenchymal stem cells through the CXCR4 receptor.
Among genotyped patients, nonresponders associated with wild-type MYD88 (show MYD88 Antibodies) and mutated CXCR4 status. Median time to response was 4 weeks
Biomarker expression in pancreatic ductal adenocarcinoma (PDAC) of CXCR4, SMAD4, SOX9 and IFIT3 will be prospectively assessed by immunohistochemistry and verified by rt.-PCR from tumor and adjacent healthy pancreatic tissue of surgical specimen.
This study explores the role of the CXCL12 (show CXCL12 Antibodies)/CXCR4 signaling pathway in primary tumor radiation response in cervical cancer and the effect on lymph node metastases. Cervical cancer xenografts derived directly from patients were treated with targeted, fractionated RT and weekly cisplatin, with or without the CXCR4 inhibitor Plerixafor
CXCR4 controls leukocyte mobilization after trauma.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1 (show CXCL12 Antibodies)/CXCR4 axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
reports transmural and perivascular expression patterns of chemokines CCL2 (show CCL2 Antibodies) and CXCL2 (show CXCL2 Antibodies) and of chemokine (show CCL1 Antibodies) receptors CCR2 (show CCR2 Antibodies), CCR5, and CXCR4 following coronary angioplasty
The current analysis failed in identifying a causal mutation on the CXCR4 gene underlying a previously reported quantitative trait loci for cattle trypanotolerance on bovine chromosome 2.
There is a potential link between follicular SDF1 (show CXCL12 Antibodies)/CXCR4 activation and the regulation of ovulation-related genes in cows and horses.
The combination of low expression of CXCR4 and high expression of IL-10 (show IL10 Antibodies) might be closely concerned with some bias for the production of PI calves.
The increased CXCR4 and CXCR7 (show CXCR7 Antibodies) expression resulted in increased SDF-1 (show CXCL12 Antibodies)-induced RF/6A cell migration and tube formation.
The CXCR7 (show CXCR7 Antibodies)/CXCR4/CXCL12 (show CXCL12 Antibodies) axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
These findings suggest that FBLN5 (show FBLN5 Antibodies) may interfere with choroidal neovascularization by downregulating VEGF (show VEGFA Antibodies), CXCR4, and TGFB1 (show TGFB1 Antibodies) expression and inhibiting choroidl endothelial cell proliferation.
Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 and CXCR4 for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 almost exclusively
Arteries are formed by vein-derived endothelial tip cells, this process critically depends on chemokine receptor Cxcr4 function.
SDF1a (show CXCL12 Antibodies) directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (show CXCR7 Antibodies).
Hoxb8a is induced by and cooperates with Wnt (show WNT2 Antibodies) signaling to up-regulate cxcr4b, and acts through multiple mechanisms to repress cxcr7b expression.
Expression of Cxcr4 and Cxcl12 (show CXCL12 Antibodies) in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12 (show CXCL12 Antibodies)/Cxcr4 pair in brain development and functioning.
show that inactivation of the estrogen receptor ESR1 (show ESR1 Antibodies) results in ectopic expression of cxcr4b throughout the primordium, whereas ESR1 (show ESR1 Antibodies) overexpression results in a reciprocal reduction in the domain of cxcr4b expression.
Study suggest that the Cxcl12a-Cxcr4b ligand-receptor pair are involved in the migration of GnRH3 neurons in zebrafish, and are therefore crucial for the development of this system.
A CXCR4-like chemokine receptor is expressed by the migrating lateral line primordium cells. Both the formation and the innervation of this system depend on the SDF1 (show CXCL12 Antibodies)-CXCR4 system.
Knocking down CXCR4 results in severe defects in primordial germ cell migration.
SDF-1 (show CXCL12 Antibodies)/CXCR4 signaling is important for guiding retinal ganglion cell axons within the retina to the optic stalk to exit the retina.
chemokine (show CCL1 Antibodies) signaling contributes to both the olfactory placode assembly and the olfactory sensory neurons axon pathfinding in zebrafish
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
C-X-C chemokine receptor type 4
, SDF-1 receptor
, Stromal cell-derived factor 1 receptor
, chemokine (C-X-C motif) receptor 4
, chemokine (C-X-C) receptor 4
, chemokine receptor 4
, leukocyte-derived seven transmembrane domain receptor
, leukocyte-expressed seven-transmembrane-domain
, pre-B-cell-derived chemokine receptor
, stromal cell-derived factor 1 receptor
, CXC chemokine receptor
, chemokine receptor (LCR1)
, CD184 antigen
, leukocyte-derived seven-transmembrane-domain receptor
, lipopolysaccharide-associated protein 3
, neuropeptide Y receptor Y3
, seven transmembrane helix receptor
, seven-transmembrane-segment receptor, spleen
, C-X-C chemokine receptor type 4-B
, SDF-1 receptor B
, SDF-1 receptor-B
, Stromal cell-derived factor 1 receptor-B
, stromal cell-derived factor 1 receptor B
, chemokine receptor CXCR4
, CXC chemokine receptor 4