anti-AXIN2 Antibodies

Protein Summary

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.

Alternative names and synonyms associated with AXIN2

• axin 2 (AXIN2) antibody
• axin 2 (conductin, axil) (axin2) antibody
• axin 2 (conductin, axil) S homeolog (axin2.S) antibody
• axin 2 (Axin2) antibody

• arp-A antibody
• Axi1 antibody
• Axil antibody
• axin-2 antibody
• axin2 antibody
• Show all synonym aliases
• Conductin antibody
• MGC81576 antibody
• ODCRCS antibody
• wu:fb37c08 antibody
• xarp antibody
• zgc:111942 antibody

Protein level used designations for anti-Axin 2 (AXIN2) Antibodies

axin-2 , axin-like protein , axis inhibition protein 2 , conductin , etID37069.3 , axin 2 (conductin, axil) , axin-related protein , axin 2 , Axin-related protein , axin-2-like