Browse our SNX13 Proteins (SNX13)

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

• sorting nexin 13 (SNX13)
• sorting nexin 13 (Snx13)

• DKFZp469H181 protein
• MGC142644 protein
• mKIAA0713 protein
• RGS-PX1 protein

sorting nexin-13 , sorting nexin 13 , sorting nexin-13-like , rgs domain- and phox domain-containing protein