Browse our anti-BMP5 (BMP5) Antibodies

Zebrafish Bone Morphogenetic Protein 5 (BMP5) interaction partners

1. zebrafish bmp5 is expressed in neural crest progenitor cells and it activates the Smad and Erk signaling pathways to regulate cell survival and proliferation, respectively.

2. Results identify bone morphogenetic proteins 2b and 5 as crucial components of the endodermal signals that induce epibranchial neurogenesis.

Cow (Bovine) Bone Morphogenetic Protein 5 (BMP5) interaction partners

1. results demonstrate that bone morphogenetic protein 5 is differentially expressed in the bovine oviductal isthmus during the estrous cycle showing that it could be a regulator of the reproductive events that occur in the bovine oviductal environment

Human Bone Morphogenetic Protein 5 (BMP5) interaction partners

1. Our results indicate significant association of rs1470527 and rs9382564 polymorphism of BMP5 gene with KOA [knee Osteoarthritis ]

2. The tumor suppressor role of BMP5 highlights its crucial role in CRC initiation and development.

3. Suggest a significant role of miR-32/BMP5 axis in colorectal cancer tumorigenesis.

4. findings suggested that BMP5 might be a potential prognostic biomarker or therapeutic target for patients with NSCLC

5. Our results showed that ASPN rs13301537 T to C change and variant C genotype may contribute to knee OA risk in a Chinese Han population.

6. Data indicate significant association between the bone morphogenetic protein 5 (BMP5) microsatellite and knee osteoarthritis (OA) in women, but not in men.

7. BMP5, is elevated in the stenotic colon segment of Hirschsprung disease patients, and BMP5 signaling may play a pivotal role in disease development.

8. BMP5 and BMP7, involved in cardiomyocyte differentiation defect

9. CASP3 rs4862396, BMP5 rs3734444 and IRS2 rs7986346 may affect the survival in patients after androgen-deprivation therapy for prostate cancer

10. BMP-5 is expressed in the tubuli of adult kidneys. Its decreased expression in nephrosclerosis along with its regenerative capabilities in HK-2 cells may point to a protective role in hypertensive nephrosclerosis.

11. Taken together, BMP4 and BMP5 simultaneously inhibit the growth and promote migration and invasion of the same pancreatic cells and thus exhibit a biphasic role with both detrimental and beneficial functions in pancreatic cancer progression

12. Variability in gene expression of BMP5 may be an important contributor to osteoarthritis genetic susceptibility

13. The expression signals of BMP-5 mRNA in malignant schwannoma were relatively lower than in benign lesions

14. BMP-5 increases the levels of osteopontin, BMP-2, alkaline phosphatase and core binding factor alpha 1 mRNAs in human periodontal (HPL) ligament cells.

15. To analyze the expression of bone morphogenetic proteins (BMPs) in prostate and breast cancers with established metastasis in bone

16. BMP5 is expressed in normal synovial tissue and was decreased in osteoarthritis and rheumatoid arthritis.

17. The differential allelic expression (DAE) of BMP5 in human mesenchymal tissues obtained from 16 donors undergoing joint replacement for treatment of osteoarthritis, was examined.

18. Approximately half of the prostate tumors displayed increased copy numbers of the BMP2, BMP5, BMP7, and UC28 gene loci, which may account for their abnormal gene expression patterns in neoplastic prostate tissue.

19. Quantitative PCR analysis revealed down-regulation of BMP2 and BMP5 in tissue samples from adrenocortical carcinoma and adrenocortical tumor cell lines compared with normal adrenal glands.

Mouse (Murine) Bone Morphogenetic Protein 5 (BMP5) interaction partners

1. Data conclude that BMP-5 has stage-specific role to play during MC3T3E1 osteoblast differentiation in part by autocrine p38/Runx2/COLIA1 signaling.

2. Bmp5 gene thus contains an "injury response" control region that is distinct from embryonic enhancers, and that is activated by multiple types of injury in adult animals

3. Early endothelial outgrowth cells act protective in diabetic nephropathy, and such effects are significantly stimulated by BMP-5

4. BMP-5 acts as a potent endothelial outgrowth cells agonist in murine AKI in the short and mid to long term

5. Bone morphogenetic protein 5 regulates the number of keratinocyte stem cells from the skin of mice.

6. Data indicate that locus coeruleus development requires either Bmp5 or Bmp7, and one is able to compensate for the loss of the other.

7. Variability in gene expression of BMP5 may be an important contributor to osteoarthritis genetic susceptibility

8. BMP5 is required not only for skeletal patterning during embryonic development, but also for bone response and remodeling to mechanical stimulation at specific anatomic sites in the skeleton

9. Bmp5 is expressed in many skeletal precursors and different enhancers control expression in individual bones.

Pig (Porcine) Bone Morphogenetic Protein 5 (BMP5) interaction partners

1. genetic association studies: SNP 131C>T in 3' untranslated region is associated with fatness traits; CC pigs have thinner back fatness & heavier hams than TC pigs; CC pigs have higher fat percentage & lower lean meat percentage than TT pigs