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anti-Human BMP5 Antibodies:
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Human Polyclonal BMP5 Primary Antibody for IHC (p), ELISA - ABIN544632
Sakaue, Kitazawa, Nishida, Kitazawa, Maeda: Molecular cloning and characterization of human bone morphogenic protein (BMP)-5 gene promoter. in Biochemical and biophysical research communications 1996
Show all 3 Pubmed References
Human Polyclonal BMP5 Primary Antibody for IHC (p), ELISA - ABIN3043800
Wang, Xue, Zhao, Liu, Ma, Ma: Form-deprivation myopia induces decreased expression of bone morphogenetic protein-2, 5 in guinea pig sclera. in International journal of ophthalmology 2015
Human Polyclonal BMP5 Primary Antibody for IF (p), IHC (p) - ABIN718871
Wu, Chen, Mi, Chen, Wang, Gao: Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients. in International journal of clinical and experimental pathology 2014
zebrafish bmp5 is expressed in neural crest progenitor cells and it activates the Smad and Erk signaling pathways to regulate cell survival and proliferation, respectively.
Results identify bone morphogenetic proteins 2b and 5 as crucial components of the endodermal signals that induce epibranchial neurogenesis.
results demonstrate that bone morphogenetic protein 5 is differentially expressed in the bovine oviductal isthmus during the estrous cycle showing that it could be a regulator of the reproductive events that occur in the bovine oviductal environment
Our results indicate significant association of rs1470527 and rs9382564 polymorphism of BMP5 gene with KOA [knee Osteoarthritis ]
The tumor suppressor role of BMP5 highlights its crucial role in CRC initiation and development.
Suggest a significant role of miR-32/BMP5 axis in colorectal cancer tumorigenesis.
findings suggested that BMP5 might be a potential prognostic biomarker or therapeutic target for patients with NSCLC
Our results showed that ASPN rs13301537 T to C change and variant C genotype may contribute to knee OA risk in a Chinese Han population.
Data indicate significant association between the bone morphogenetic protein 5 (BMP5) microsatellite and knee osteoarthritis (OA) in women, but not in men.
BMP5, is elevated in the stenotic colon segment of Hirschsprung disease patients, and BMP5 signaling may play a pivotal role in disease development.
BMP5 and BMP7, involved in cardiomyocyte differentiation defect
CASP3 rs4862396, BMP5 rs3734444 and IRS2 rs7986346 may affect the survival in patients after androgen-deprivation therapy for prostate cancer
BMP-5 is expressed in the tubuli of adult kidneys. Its decreased expression in nephrosclerosis along with its regenerative capabilities in HK-2 cells may point to a protective role in hypertensive nephrosclerosis.
Taken together, BMP4 and BMP5 simultaneously inhibit the growth and promote migration and invasion of the same pancreatic cells and thus exhibit a biphasic role with both detrimental and beneficial functions in pancreatic cancer progression
Variability in gene expression of BMP5 may be an important contributor to osteoarthritis genetic susceptibility
The expression signals of BMP-5 mRNA in malignant schwannoma were relatively lower than in benign lesions
BMP-5 increases the levels of osteopontin, BMP-2, alkaline phosphatase and core binding factor alpha 1 mRNAs in human periodontal (HPL) ligament cells.
To analyze the expression of bone morphogenetic proteins (BMPs) in prostate and breast cancers with established metastasis in bone
BMP5 is expressed in normal synovial tissue and was decreased in osteoarthritis and rheumatoid arthritis.
The differential allelic expression (DAE) of BMP5 in human mesenchymal tissues obtained from 16 donors undergoing joint replacement for treatment of osteoarthritis, was examined.
Approximately half of the prostate tumors displayed increased copy numbers of the BMP2, BMP5, BMP7, and UC28 gene loci, which may account for their abnormal gene expression patterns in neoplastic prostate tissue.
Quantitative PCR analysis revealed down-regulation of BMP2 and BMP5 in tissue samples from adrenocortical carcinoma and adrenocortical tumor cell lines compared with normal adrenal glands.
Data conclude that BMP-5 has stage-specific role to play during MC3T3E1 osteoblast differentiation in part by autocrine p38/Runx2/COLIA1 signaling.
Bmp5 gene thus contains an "injury response" control region that is distinct from embryonic enhancers, and that is activated by multiple types of injury in adult animals
Early endothelial outgrowth cells act protective in diabetic nephropathy, and such effects are significantly stimulated by BMP-5
BMP-5 acts as a potent endothelial outgrowth cells agonist in murine AKI in the short and mid to long term
Bone morphogenetic protein 5 regulates the number of keratinocyte stem cells from the skin of mice.
Data indicate that locus coeruleus development requires either Bmp5 or Bmp7, and one is able to compensate for the loss of the other.
BMP5 is required not only for skeletal patterning during embryonic development, but also for bone response and remodeling to mechanical stimulation at specific anatomic sites in the skeleton
Bmp5 is expressed in many skeletal precursors and different enhancers control expression in individual bones.
genetic association studies: SNP 131C>T in 3' untranslated region is associated with fatness traits; CC pigs have thinner back fatness & heavier hams than TC pigs; CC pigs have higher fat percentage & lower lean meat percentage than TT pigs
This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
bone morphogenetic protein 5
, bone morphogenetic protein 5-like
, bone morphogenenic protein-5
, short ear