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Human IL23A Protein expressed in Wheat germ - ABIN1307786
Wang, Zhong, Zheng, Li, Chen, Ma, Sun, Yan, Li: Damage effect of interleukin (IL)-23 on oxygen-glucose-deprived cells of the neurovascular unit via IL-23 receptor. in Neuroscience 2015
IL-23 binding to its receptor promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition through the STAT3 (show STAT3 Proteins) signaling pathway.
TNF-alpha (show TNF Proteins) plays an important role for the autocrine stimulation of IL-23 production by 6-sulfo LacNAc(+) dendritic cells.
The expression of IL-17 (show IL17A Proteins) and IL-12 (show IL12A Proteins) in patients with lupus miliaris disseminatus faciei is reported in patients and healthy controls.
SIGIRR (show SIGIRR Proteins) is both a negative regulator of TLR4 (show TLR4 Proteins) and a positive regulator of TLR7 (show TLR7 Proteins)/8.
interleukin 23 (IL-23)/T-helper 17 (TH 17) immune axis has been identified as a major immune pathway in psoriasis disease pathogenesis
Serum IL-17 (show IL17A Proteins) and IL-23 values positively correlated with serum total IgE levels. Serum levels of IL-10 (show IL10 Proteins) were lower in children with atopy and dyslipidemia than patients with dyslipidemia.
IL-23/IL-17 (show IL17A Proteins) axis and biochemical markers in the pathogenesis of Type 2 Diabetes
Higher levels of TGF-beta (show TGFB1 Proteins) mRNA were observed in biopsies taken from healthy controls, and the IL-23 mRNA levels were significantly increased in the peri (show PLIN1 Proteins)-implantitis group (P < 0.0001). No differences in IL-17 (show IL17A Proteins) mRNA levels were observed between the two groups (P > 0.05).
clinical significance of IL-17 (show IL17A Proteins) and IL-23 in the pathogenesis of different types of gastric neoplasms in humans, is reported.
this study shows neuroprotective effects of G-CSF (show CSF3 Proteins) administration in microglia-mediated reactive T cell activation in vitro in a mouse model
This study defines a critical IL-36/IL-23/IL-22 (show IL22 Proteins) cytokine network instrumental for antimicrobial peptide (show CAMP Proteins) production and host defense in intestinal mucosa damage using a mouse inflammatory bowel disease model.
IL-23 drives differentiation of peripheral gamma-delta 17 T cells from adult bone marrow-derived precursors.
In mice on a C57BL/6 background, neither IL-23p19 nor IL-17A (show IL17A Proteins) plays a role for immune protection against L. major in the physiological context of natural infections.
The hormone levels are significantly reduced and lymphocytic infiltration in the lacrimal gland in ovariectomized mice, whereas the frequency of Th17 cells in the blood and spleen and IL-17A (show IL17A Proteins) and IL-23 expression in the lacrimal glands are increased, leading to reduced tear production and positive fluorescein staining in the cornea.
this study unveiled the role of IL-23-dependent IL-17 (show IL17A Proteins) induction in LdCen-/- parasite-induced immunity and subsequent protection against visceral leishmaniasis
Results reveal the importance of the IL-23/IL-17 (show IL17A Proteins) inflammatory axis in secondary brain injury after intracerebral hemorrhage.
RIG-I (show DDX58 Proteins) expression is markedly increased in the affected skin derived from psoriasis patients and from both IL-23- and imiquimod -induced psoriasis-like mouse model.
results show that IL-23 accounts for the main aspects of human and murine lupus including the expansion of double negative T cells, decreased IL-2 (show IL2 Proteins), and increased IL-17 (show IL17A Proteins) production
this study shows that IL-23 but not IL-1 (show IL1A Proteins) contributes to the IL-17A (show IL17A Proteins) expression induced by subacute O3 exposure
IL-23 released by keratinocytes in response to endogenous TLR4 (show TLR4 Proteins) ligands causes skin DCs, which selectively express IL-23R (show IL23R Proteins), to up-regulate their endogenous IL-23 production and drive an IL-22 (show IL22 Proteins) response in naive CD4 (show CD4 Proteins)(+) T cells that mediates epidermal thickening.
These results provide genetic information about both swine IL-23 the IL-23 receptor alpha (IL-23Ralpha) and IL-12 receptor beta1 (IL-12Rbeta1), which allows for better understanding of interleukin systems involved in pig immunity.
cloning and characterization of interleukin-17 (show IL17A Proteins) expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells
This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Proteins) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
IL-23 subunit alpha
, JKA3 induced upon T-cell activation
, interleukin 23 p19 subunit
, interleukin-23 subunit alpha
, interleukin-23 subunit p19
, interleukin-six, G-CSF related factor
, IL-23 p19 subunit
, Interleukin-23 p19 subunit
, interleukin 23 p19