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High GLIPR1 expression is associated with cisplatin resistance in lung cancer.
The present study identified GLIPR1 and miR-16 (show GDE1 ELISA Kits) as key components for regulating the proliferation, migration, invasion and cancer-initiating cells in osteosarcoma
This study reveals a novel pathway that PRMT5 (show PRMT5 ELISA Kits)/WDR77 (show WDR77 ELISA Kits) regulates GLIPR1 expression to control lung cancer cell growth.
Overexpression of RTVP-1 in human neural stem cells induced mesenchymal differentiation, whereas silencing of RTVP-1 in glioma stem cells (GSCs) decreased the mesenchymal transformation and stemness of these cells.
RTVP-1 regulates glioma cell spreading, migration and invasion and that these effects are mediated via interaction with N-WASP and by interfering with the inhibitory effect of hnRNPK (show HNRNPK ELISA Kits) on the function of this protein.
Data indicate that combining adenoviral vector-mediated GLIPR1 gene therap (AdGLIPR1) with radiotherapy may achieve additive or synergistic tumor control in selected prostate and bladder tumors.
Based on the observed overexpression in AML (show RUNX1 ELISA Kits) samples, GliPR1 should be further explored as a potential target for AML (show RUNX1 ELISA Kits)
miR (show MLXIP ELISA Kits)-137 inhibits Glioblastom stem cell self-renewal and promotes their differentiation by targeting RTVP-1 which down-regulates CXCR4 (show CXCR4 ELISA Kits).
GLIPR1 interacts with Hsc70 (show HSPA8 ELISA Kits), and GLIPR1 overexpression or Hsc70 (show HSPA8 ELISA Kits) knockdown leads to transcriptional suppression of AURKA (show AURKA ELISA Kits) and TPX2 (show TPX2 ELISA Kits).
GLIPR1 core structure has a conserved central cavity via which CAP proteins are likely to bind to shared ligands.
The genetic variation is a key determining factor for the alternative splicing events in the Gli1 (show GLI1 ELISA Kits) 5' UTRs, which have functional implications on translational efficiency.
Identification of a novel mouse gene, mRTVP-1, as a p53 (show TP53 ELISA Kits) target gene. The mRTVP-1 protein has 255 amino acids and differs from the human RTVP-1 protein by two short in-frame deletions of two and nine amino acids. (mRTVP-1)
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.
GLI pathogenesis-related 1 (glioma)
, glioma pathogenesis-related protein 1
, gliPR 1
, protein RTVP-1
, related to testis-specific, vespid, and pathogenesis proteins 1
, testes-specific vespid and pathogenesis protein 1
, related to testes-specific, vespid, and pathogenesis proteins
, GLI pathogenesis-related 1
, glioma pathogenesis-related protein