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Increased serum levels of S100B (show S100B Antibodies) protein (and NSE (show ENO2 Antibodies)) were observed postoperatively in patients with postoperative cognitive dysfunction.
high S100B (show S100B Antibodies) expression in Multiple Sclerosis (MS) patient samples suggests its usefulness as a diagnostic biomarker for MS.
the underlying mechanism of S100B (show S100B Antibodies)-mediated effects on cancer stem-like cell stemness was not dependent on its binding with a receptor for advanced glycation end products (RAGE (show AGER Antibodies)), but might be through intracellular regulation, through the inhibition of p53 (show TP53 Antibodies) expression and phosphorylation.
Data show that a high serum S100beta protein level, hypertension, and high low density lipoprotein-cholesterol (LDL-C) level were the independent risk factors for cerebral small vessel disease (SVD (show KCNJ13 Antibodies)).
the serum concentrations of S100B (show S100B Antibodies) are increased in bipolar disorder patients.
Levels of NSE (show ENO2 Antibodies) and S100B (show S100B Antibodies) are still elevated 1 year postpartum in women who have had preeclampsia in contrast to women with previous normal pregnancies.
In vitro experiments using repeated freeze-thaw procedures showed an intracellular up-regulation of S100B (show S100B Antibodies) in normal and vitiligo (show MITF Antibodies) melanocytes before an extensive release in the environment.
Acute paranoid schizophrenia inpatients present a day/night change of S100B (show S100B Antibodies) serum levels at admission that disappears at discharge.
Compared to the control, the S100B (show S100B Antibodies)/GAPDH (show GAPDH Antibodies) mRNA ratio was significantly decreased in chronic liver diseases (p = 0.006) and most decreased in chronic hepatitis C patients (p = 0.023). We here evaluated S100B (show S100B Antibodies) expression as a marker of hepatic nerves in patients with various chronic liver diseases, topographically and semi-quantitatively.
results indicate there were decreased S100B (show S100B Antibodies) serum levels in bipolar patients in a manic phase after treatment.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21\; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
S-100 calcium-binding protein, beta chain
, S-100 protein subunit beta
, S100 calcium-binding protein, beta (neural)
, protein S100-B