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anti-Human EHD1 Antibodies:
anti-Mouse (Murine) EHD1 Antibodies:
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Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Results suggest that EHD1 is a cisplatin (CDDP)-resistant gene that suppresses DNA adduct-induced apoptosis by modulating intracellular CDDP concentrations.
this study shows that overexpression of EHD1 induced the epithelial-mesenchymal transition and increased the metastatic potential of lung cancer cells in vitro and in vivo
RAB11FIP3 (show RAB11FIP3 Antibodies) combines with Eps15 (show EPS15 Antibodies) homology domain 1 to promote the endocytosis recycling of phosphorylation of epithelial growth factor receptor (show RYK Antibodies).
van (show TNIP1 Antibodies) der (show GDF3 Antibodies) Waals interactions should be the main consideration when we design peptide inhibitors of EHD1 EH domain with high affinities.
Authors found that Eps15-homology domain 1 (EHD1), a protein that associates with the endocytic recycling compartment (ERC), colocalizes with active R-Ras in transiently expressed HeLa cells.
that Molecule Interacting with CasL (show NEDD9 Antibodies) Like-1 and Eps15 (show EPS15 Antibodies) Homology Domain protein 1 differentially influence microtubule dynamics during early and late mitosis
Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase.
Data indicate that concordant transforming growth factor-beta1 (TGFbeta (show TGFB1 Antibodies)-1) positive and EH-domain containing 1 (EHD1) negative as a strong favorable prognosis factor in non-small cell lung cancer (NSCLC).
MICAL-L1 (show MICALL1 Antibodies)-mediated recruitment of EHD1 to Src (show SRC Antibodies)-containing recycling endosomes is required for the release of Src (show SRC Antibodies) from the perinuclear endocytic recycling compartment in response to growth factor stimulation.
evidence that the functions of both EHD1 and EHD4 (show EHD4 Antibodies) are primarily in TRE (show TREH Antibodies) membrane vesiculation, whereas EHD3 (show EHD3 Antibodies) is a membrane-tubulating protein.
EHD1, EHD2 (show EHD3 Antibodies), and EHD4 (show EHD4 Antibodies) are recruited to caveolae. Recruitment of the other EHDs increases markedly when EHD2 (show EHD3 Antibodies), which has been previously detected at caveolae, is absent. Construction of knockout cell lines lacking EHDs 1, 2, and 4 confirms this apparent functional redundancy.
These findings reveal a novel and functionally important role for EHD1 in governing CSF-1R (show CSF1R Antibodies) signalling via regulation of anterograde transport of CSF-1R (show CSF1R Antibodies) to the macrophage cell surface.
regulates the maintenance of T-tubules through its interaction with BIN1 (show BIN1 Antibodies)
these data reveal a unique role for EHD1 in early lens development.
Early steps in primary cilium assembly require EHD1/EHD3 (show EHD3 Antibodies)-dependent ciliary vesicle formation.
tubule formation in myoblasts relies on a functional EHD1 ATPase (show DNAH8 Antibodies) domain. EHD1 regulates BIN1 (show BIN1 Antibodies) induced tubule formation.
The characterization of Fer1L5 and its interaction with EHD1 and EHD2 (show EHD3 Antibodies) underscores the complex requirement of ferlin proteins and mediators of endocytic recycling for membrane trafficking events during myotube formation
Histopathology revealed abnormal spermatogenesis in the seminiferous tubules and the absence of mature spermatozoa in the epididymides of Ehd1-/- males.
EHD3 (show EHD3 Antibodies): a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1.
EHD1 and EHBP1 (show EHBP1 Antibodies), but not EHD2 (show EHD3 Antibodies), are required for perinuclear localization of GLUT4 (show SLC2A4 Antibodies) and reveal that loss of EHBP1 (show EHBP1 Antibodies) disrupts insulin (show INS Antibodies)-regulated GLUT4 (show SLC2A4 Antibodies) recycling in cultured adipocytes.
This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors.
EH domain-containing protein 1
, EH-domain containing 1
, EH-domain containing 3, like
, EH-domain-containing protein 1
, PAST homolog 1