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muscle-specific (show EIF3K Proteins) expression of myogenin in zebrafish embryos is controlled by multiple regulatory elements in the promoter
The results show that myogenin gene expression is more sensitive to nutrient conditions of fish than traditional indicators such as the RNA/DNA ratio.
myog cannot rescue myogenesis in the myod (show MYOD1 Proteins)/myf5 (show MYF5 Proteins) double morphant
Autophagy proteins were measured to understand the molecule mechanisms. We also inhibited hypoxic autophagy and examined the changes in myogenin expression, myotubes formation, and apoptosis.
The ELF-EMFs did not affect C2C12 myoblast viability or proliferation rate. Conversely, at ELF-EMF intensity in the mT range, the myogenic process was accelerated, through increased expression of MyoD (show MYOD1 Proteins), myogenin, and connexin 43 (show GJA1 Proteins)
Data show that MyoD (show MYOD1 Proteins) and myogenin associate with distinct chromatin states.
The study demonstrates an essential role of Setd2 in myoblast proliferation and differentiation, and uncovers Setd2-mediated molecular mechanism through regulating MyoG and p21.
Overexpression and knockdown of TLP revealed that the levels of muscle-specific myosin heavy chain and the myogenic transcription factor myogenin are downregulated by TLP. The proximal AT-rich sequence of the myogenin promoter is responsible for TLP-mediated transcriptional repression.
This suggests that 4.1R (show EPB41 Proteins) may influence myogenesis by preventing VHL (show VHL Proteins)-mediated myogenin degradation.
Findings indicate a interplay between A-kinase anchoring protein (show MYRIP Proteins) 6 (AKAP6) and myogenin.
In summary, our results implicate that metastatic properties of some RMS subtypes might be linked to c-Myb (show MYB Proteins) function.
The Myf5 (show MYF5 Proteins)- and Myogenin-deficient mice showed a partial or complete, respectively, loss of TMC (show STT3A Proteins) in an otherwise regularly structured thymus.
Dach2 (show DACH2 Proteins) and Hdac9 (show HDAC9 Proteins) mediate the effects of muscle activity on muscle reinnervation; Myog and Gdf5 (show GDF5 Proteins) appear to stimulate muscle reinnervation through parallel pathways
Findings indicate a interplay between A-kinase anchoring protein 6 (AKAP6) and myogenin.
results indicate that myogenin is a positive regulator in transcriptional regulation of MEGF10 (show MEGF10 Proteins) in skeletal muscle
Sustained GSK3beta activity represses a critical regulatory step in the myogenic cascade, contributing to the undifferentiated, proliferative phenotype in alveolar rhabdomyosarcoma.
Our study illustrates that focal myogenin immunoreactivity occurs uncommonly in fibroepithelial polyps of the lower female genital tract.
Data indicate that muscle MYOG mRNA expression doubled, whereas MSTN (show MSTN Proteins) protein expression decreased following immobilization.
SREBP-1 (show SREBF1 Proteins) regulate muscle protein synthesis through the downregulation of the expression of MYOD1 (show MYOD1 Proteins), MYOG and MEF2C (show MEF2C Proteins) factors.
the FACT complex promotes myogenin-dependent transcription
Human muscle samples were analysed at different time-points post-denervation to evaluate changes in myogenin expression and their relationship with skeletal muscle atrophy.
After 2 years of denervation, expression of myogenin protein in myonuclei was decreased, but after 3 years of denervation, no expression of myogenin protein in myonuclei was found in denervated posterior cricoarytenoid muscles.
The physical interaction of CARM1 (show CARM1 Proteins) and PCAF (show KAT2B Proteins) is likely pivotal for the activation of PCAF (show KAT2B Proteins) in the downstream of CARM1 (show CARM1 Proteins) pathway for inducing myogenin under Tetradecanoylphorbol Acetate -induced differentiation.
Studied the effects of microRNA-27a on myogenin expression and the Akt (show AKT1 Proteins)/FoxO1 (show FOXO1 Proteins) signal pathway during porcine myoblast differentiation. Overexpression of miR (show MYLIP Proteins)-27a suppressed myogenin expression during porcine myoblast differentiation, whereas inhibition of miR (show MYLIP Proteins)-27a promoted the mRNA and protein expression levels of myogenin; overexpression of miR (show MYLIP Proteins)-27a decreased the level of P-Akt/Akt (show AKT1 Proteins) and increased the protein level of FoxO1 (show FOXO1 Proteins).
the MyoG gene is very conservative and there are very few mutation sites between different breeds
mutation in exon 1 of the MYOG gene had no statistically significant association with carcass quality traits
Significant differences were found in the birth weight and the backfat thickness among the different MyoG genotypes
Relative MYOD1 (show MYOD1 Proteins) expression was not different, but MYOG expression was higher in the (ligated-tube)crowded group embryos.
MiR (show MYLIP Proteins)-2425-5p targets RAD9A (show RAD9A Proteins) and MYOG to regulate the proliferation and differentiation of bovine skeletal muscle-derived satellite cells.
EGR1 (show EGR1 Proteins) can promote skeletal muscle satellite cell differentiation through positive regulation of MyoG gene expression.
data suggested that miR (show MYLIP Proteins)-2400 could promote MDSCs proliferation through targeting MYOG
the MyoG SNP has potential as a genetic marker for economically relevant body measurement traits in native Chinese cattle breeds.
Studied and compared mRNA levels of myostatin (MSTN (show MSTN Proteins)), myogenin (MyoG), and myosin heavy chain (MyHC) in skeletal muscles of two rabbit breeds with different body sizes and growth rates.
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle.
, myogenin (myogenic factor 4)
, MYOD1-related protein
, class C basic helix-loop-helix protein 3
, myogenic factor 4
, myogenic factor