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Human CD9 ELISA Kit for Sandwich ELISA - ABIN812211
Bhargava, Becker, Viken, Jagtap, Dey, Steinbach, Wu, Kumar, Bitterman, Ingbar, Wendt: Proteomic profiles in acute respiratory distress syndrome differentiates survivors from non-survivors. in PLoS ONE 2014
CD9 regulates the T cell-stimulatory capacity of granulocyte-macrophage colony-stimulating factor (GM-CSF (show CSF2 ELISA Kits))-dependent bone marrow-derived Dendritic Cells (BMDCs), without affecting antigen presentation by fms-like tyrosine kinase 3 ligand (Flt3L)-dependent BMDCs.
DPP4:CD9:TTSP as the protein complexes are necessary for early efficient MERS-coronavirus entry.
Our results indicate that the suppression of cartilage degradation in CD9(-/-) could be in part related to an increase in the expression of the two main cartilage extracellular matrix proteins aggrecan (show ACAN ELISA Kits) and type II collagen (show COL2A1 ELISA Kits).
Tetraspanin CD9 and ectonucleotidase CD73 identify an osteochondroprogenitor population with elevated osteogenic properties.
Data indicate that anti-inflammatory effects of statins are CD9-dependent.
study demonstrates ablation of Cd9 had no detectable effect on de novo primary proatate tumour onset, but did significantly increase metastasis to the liver but not the lungs
In vitro myotubes lacking CD9P-1 (show PTGFRN ELISA Kits) or both CD9 and CD81 (show CD81 ELISA Kits) fuse with a higher frequency than normal myotubes
chemotaxis toward antigen is controlled in mast cells by a cross-talk among FcepsilonRI, tetraspanin CD9, transmembrane adaptor proteins NTAL and LAT, and cytoskeleton-regulatory proteins of the ERM family
tetraspanin CD9 modulates molecular organization of integrins in lymphatic endothelial cells, thereby supporting several functions required for lymphangiogenesis
Tetraspanin family member CD9 plays an important role in sperm-egg fusion.
CD9 stabilizes gp130 (show IL6ST ELISA Kits) by blocking its ubiquitin-dependent lysosomal degradation to promote the IL6 (show IL6 ELISA Kits)-gp130 (show IL6ST ELISA Kits)-bone marrow X-linked non-receptor tyrosine kinase (show TNK1 ELISA Kits)-STAT3 (show STAT3 ELISA Kits) signaling for maintaining GSC (show GSC ELISA Kits) selfrenewal and tumorigenic capacity.
CD9 was highly expressed on extravillous trophoblast (EVT) at the boundary region of EVT invasion and intravascular EVT. CD9 expression on Swan71 cells was reduced under hypoxic conditions, while its expression was increased by co-culture with HUVEC. CD9 could attenuate EVT invasion under the influence of an oxygen environment and maternal endothelial cells, proposing CD9 as a potential regulator of human placentation.
As for 18Lin(-), CD34 (show CD34 ELISA Kits)(-) HSCs are characterized by low expression of the tetraspanin CD9, which promotes homing, and high expression of the peptidase CD26 (show DPP4 ELISA Kits), which inhibits homing.
The findings suggest that, in contrast with previous models, the ligand-binding site of integrin alphaVbeta3 (show ITGAV ELISA Kits), binds to the constant region (helices A and B) of the EC2 (show TCF15 ELISA Kits) domain of CD9, CD81 (show CD81 ELISA Kits), and CD151 (show CD151 ELISA Kits) antigens.
Data suggest that CD9 should be further evaluated as a target for glioblastoma treatment.
Collectively, using tetraspanin CD9 in tandem with E-cadherin (show CDH1 ELISA Kits) as a biomarker in renal cell carcinoma will help to not only distinguish between types, but also predict the metastatic potential of RCC (show XRCC1 ELISA Kits).
Data indicate that CD9 is implicated in BCC invasiveness and metastases by cellular mechanisms that involve specific CD9+ plasma membrane protrusions of BCCs.
CD9-enriched microdomains negatively regulate LPS (show IRF6 ELISA Kits)-induced receptor formation by preventing CD14 (show NDUFA2 ELISA Kits) from accumulating into lipid rafts. [Review]
Results indicate that CD9 downregulation promoted pancreatic cancer cell proliferation and migration through at least in part, enhancing the cell surface expression of EGFR (show EGFR ELISA Kits).
CD9 expression is upregulated and its expression is correlated with tumor stage and lymph node metastasis in esophageal squamous cell carcinoma patients
Tests showed that the vitrification/warming procedures significantly decreased CD9 expression at the mRNA and protein levels, and changed the CD9 distribution pattern in bovine oocytes.
Immortalized microvascular endothelial cells of the bovine retina express members of the tetraspanin family of which CD9 was demonstrated to have a function in migration and adhesion of these cells.
CD9 present on bovine matured oocytes is involved in sperm-oocyte interaction during fertilization.
analysis of tetraspanin CD9 distribution in normal porcine tissues
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.
, BA-2/p24 antigen
, CD9 antigen
, CD9 antigen (p24)
, cell growth-inhibiting gene 2 protein
, leukocyte antigen MIC3
, motility related protein-1