Protein Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with DDX3X

• DEAD-box helicase 3, X-linked (DDX3X) antibody
• DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked (Ddx3x) antibody
• DEAD-box helicase 3, X-linked (Ddx3x) antibody
• DEAD-box helicase 3, X-linked L homeolog (ddx3x.L) antibody
• DEAD-box helicase 3, X-linked (ddx3x) antibody

• An3 antibody
• D1Pas1-rs2 antibody
• DBX antibody
• Ddx3 antibody
• DDX3X antibody
• Show all synonym aliases
• DDX14 antibody
• Fin14 antibody
• HLP2 antibody
• pl10 antibody

Protein level used designations for DDX3X

ATP-dependent RNA helicase DDX3X , CAP-Rf , DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked , DEAD box protein 3, X-chromosomal , DEAD box, X isoform , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 , DEAD/H box-3 , helicase like protein 2 , helicase-like protein 2 , D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3 , D1Pas1-related sequence 2 , DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3 , DEAD box RNA helicase DEAD3 , DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2) , embryonic RNA helicase , fibroblast growth factor inducible 14 , mDEAD3 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked , ATP-dependent RNA helicase DDX3X-like