Browse our EIF2A Proteins (EIF2A)

Full name:: Eukaryotic Translation Initiation Factor 2A, 65kDa Proteins (EIF2A)

On www.antibodies-online.com are 6 Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) Proteins from 3 different suppliers available. Additionally we are shipping EIF2A Antibodies (170) and EIF2A Kits (15) and many more products for this protein. A total of 195 EIF2A products are currently listed.

Synonyms:: ATEIF2-A2, CG9946, D030048D22, D3Ertd194e, DDBDRAFT_0185936, DDBDRAFT_0234177, DDB_0185936, DDB_0234177, deIF2alpha, Dmel\\CG9946, eIF-2, eIF-2 a, eIF-2 alpha, EIF-2A, eiF-2alpha, eIF2 alpha, EIF2-A2, eIF2-alpha, eIF2a, eIF2alpha, elF2alpha, eukaryotic translation initiation factor 2 alpha subunit, IF2A_DROME, im:7145971, l(1)14Cf, l(1)19-153, M(1)8e3-10, M(1)14C, M(1)19-153, MST089, MSTP004, MSTP089, zgc:110460

list all proteins	Gene Name	GeneID	UniProt
	EIF2A	83939	Q9BY44
	EIF2A	229317	Q8BJW6
Rat EIF2A	EIF2A	502531
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EIF2A Proteins (EIF2A) by Origin

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More Proteins for EIF2A Interaction Partners

Arabidopsis thaliana Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

The in vitro assays demonstrate the binding of the C-terminus of AtGCN2 to uncharged tRNA molecules and the enzymatic activities of AtGCN2 on both eIF2alpha homologues in A. thaliana.

Human Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF-2a ubiquitylation and degradation.
POSTN (show POSTN Proteins) may function as a protective factor for osteoblasts during this process by inhibiting the eIF2alphaATF4 pathway.
findings indicate that MSI1 (show MSI1 Proteins) plays a leading role in stress granule formation that grants cancer stem cell properties and chemoresistant stress granules in GBM, in response to stressful conditions via the PKR (show PKLR Proteins)/eIF2alpha signalling cascade.
There was no statistically significant difference in IFN therapeutic effectiveness among the patients with different genotypes of eIF-2a (show EIF2S1 Proteins)-reg2 (show FLOT1 Proteins).

Mouse (Murine) Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF-2a ubiquitylation and degradation.
ER stress is induced early in EAE and that modulation of ER stress by inhibition of eIF2alpha-CHOP (show DDIT3 Proteins) and activation of XBP-1 (show XBP1 Proteins) in RGC specifically, protects RGC somata and axons and preserves visual function.
alpha-asarone abrogated 7beta-hydroxycholesterol-triggered eIF2alpha-CHOP (show DDIT3 Proteins) activation, and enhanced macrophage beclin1 (show BECN1 Proteins) dependent autophagy.
In response to endoplasmic reticulum stress, activation of PERK (show EIF2AK3 Proteins) coordinates the integrated stress response by phosphorylating eIF2alpha, which is then quickly dephosphorylated by the GADD34 (show PPP1R15A Proteins) complex. Data imply dual role of the ISR in promoting and inhibiting medulloblastoma tumorigenesis.
stress granule formation is a downstream event of eIF2alpha phosphorylation that may not directly protect cells from apoptosis, at least in spermatocytes of seminiferous tubules in early stages.
results further extended the understanding of Heme-regulated eIF2alpha kinase on the regulation of non-erythroid lineages and might provide new aspects for preventing and treating Cd-induced detrimental effects
Data, including data from studies using cells from knockout mice, suggest that gasotransmitter H(2)S up-regulates eIF2a phosphorylation by inhibiting PPP1CA (show PPP1CA Proteins) via persulfidation, which in turn leads to transient suppression of global translation and activation of Atf4 (show ATF4 Proteins) expression. (eIF2a = eukaryotic initiation factor-2alpha (show EIF2S1 Proteins); PPP1CA (show PPP1CA Proteins) = protein phosphatase 1 catalytic subunit alpha; Atf4 (show ATF4 Proteins) = activating transcription factor 4 (show ATF4 Proteins))
Results mechanistically link multiple forms of dystonia and put forth a new overall cellular mechanism for dystonia pathogenesis, impairment of eIF2alpha signaling, a pathway known for its roles in cellular stress responses and synaptic plasticity.
The eIF2A knock out mice strain is viable and to date displays no apparent phenotype.
Thus, during addiction, cocaine hijacks translational control by p-eIF2alpha, initiating synaptic potentiation and addiction-related behaviors.

Zebrafish Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

Both DrPKZ-A and DrPKZ-B isoforms functionally interact with eIF2alpha and inhibit protein synthesis in Danio rerio.

Pig (Porcine) Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

Taken together, these results demonstrate that Porcine reproductive and respiratory syndrome virus infection induces host translation shutoff and that nsp2 (show RTN2 Proteins) is associated with this process. Both eIF2alpha phosphorylation and the attenuation of the mTOR (show FRAP1 Proteins) signaling pathway contribute to the virus-induced host translation arrest.

Fruit Fly (Drosophila melanogaster) Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

Therapeutic modulation of eIF2alpha (show EIF2S1 Proteins) phosphorylation rescues TDP-43 (show TARDBP Proteins) toxicity in amyotrophic lateral sclerosis disease models.

EIF2A Protein Profile

Protein Summary

EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002

Alternative names and synonyms associated with EIF2A

eukaryotic translation initiation factor 2 alpha subunit (EIF2 ALPHA)
eukaryotic translation initiation factor 2A (EIF2A)
eukaryotic translation initiation factor 2A (Eif2a)
eukaryotic translation initiation factor 2A (eif2a)
eukaryotic translation initiation factor 2A (eIF2a)
eukaryotic translation initiation factor 2A, 65kDa (Eif2a)
eukaryotic translation initiation factor 2A S homeolog (eif2a.S)
eukaryotic translation initiation factor (eif2A)
eukaryotic translation initiation factor (EIF2A)
eukaryotic translation Initiation Factor 2alpha (eIF-2alpha)

ATEIF2-A2 protein
CG9946 protein
D030048D22 protein
D3Ertd194e protein
DDBDRAFT_0185936 protein
DDBDRAFT_0234177 protein
DDB_0185936 protein
DDB_0234177 protein
deIF2alpha protein
Dmel\\CG9946 protein
eIF-2 protein
eIF-2 a protein
eIF-2 alpha protein
EIF-2A protein
eiF-2alpha protein
eIF2 alpha protein
EIF2-A2 protein
eIF2-alpha protein
eIF2a protein
eIF2alpha protein
elF2alpha protein
eukaryotic translation initiation factor 2 alpha subunit protein
IF2A_DROME protein
im:7145971 protein
l(1)14Cf protein
l(1)19-153 protein
M(1)8e3-10 protein
M(1)14C protein
M(1)19-153 protein
MST089 protein
MSTP004 protein
MSTP089 protein
zgc:110460 protein

Protein level used designations for EIF2A

65 kDa eukaryotic translation initiation factor 2A , eukaryotic translation initiation factor 2A , eIF-2A , Eukaryotic translation initiation factor 2A , eukaryotic translation initiation factor 2A, 65kDa , eukaryotic translation initiation factor , eukaryotic translation initiation factor 2A-like , CG9946-PA , eIF-2alpha-PA , eukaryotic initiation factor 2alpha , eukaryotic translation initiation factor 2 , eukaryotic translation initiation factor 2alpha , minute (1) 14C

GENE ID	SPECIES
830430	Arabidopsis thaliana
83939	Homo sapiens
614746	Bos taurus
229317	Mus musculus
425042	Gallus gallus
502531	Rattus norvegicus
573991	Danio rerio
8624518	Dictyostelium discoideum AX4
100120837	Nasonia vitripennis
100195059	Salmo salar
398445	Xenopus laevis
470965	Pan troglodytes
477112	Canis lupus familiaris
710497	Macaca mulatta
9625673	Volvox carteri f. nagariensis
9681594	Micromonas pusilla CCMP1545
100050507	Equus caballus
100145715	Xenopus (Silurana) tropicalis
100338417	Oryctolagus cuniculus
100398797	Callithrix jacchus
100481938	Ailuropoda melanoleuca
100622221	Sus scrofa
100721181	Cavia porcellus
32617	Drosophila melanogaster
101119523	Ovis aries

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