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This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
RNA binding motif protein 5
, RNA-binding motif protein 5-B
, RNA-binding protein 5-B
, RNA-binding motif protein 5
, RNA-binding protein 5
, RNA-binding protein 5-like
, RNA-binding motif protein 5-A
, RNA-binding protein 5-A
, putative tumor suppressor LUCA15
, renal carcinoma antigen NY-REN-9
, G15 protein
, tumor suppressor LUCA15