SMN1 Proteins

10 Survival of Motor Neuron 1, Telomeric (SMN1) Proteins from 4 manufacturers are available on www.antibodies-online.com.

Data Quality
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Type
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    Protein
Target
  • 10
    Survival of Motor Neuron 1, Telomeric (SMN1)
  • 603
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Application
  • 10
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Reactivity
  • 4
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  • 1
Host
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  • 3
  • 1
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Binding Specificity
  • 2
  • 2
  • 2
  • 1
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Conjugate
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Protein Type
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Format
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Suggested next Filters
10 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3134732
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1320585
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1320587
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1320589
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity ≥ 98 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN4989095
$688.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCow
Application ELISA
Order details Cat. No. ABIN1460985
$2,755.50
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityDog
Application ELISA
Order details Cat. No. ABIN1461410
$2,755.50
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityRat
Application ELISA
Order details Cat. No. ABIN1475468
$2,762.83
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCat
Application ELISA
Order details Cat. No. ABIN1636281
$2,764.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCynomolgus
Application ELISA
Order details Cat. No. ABIN1631650
$2,775.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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SMN1 Protein Profile

Protein Summary

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. However, mutations in this gene, the telomeric copy, are associated with spinal muscular atrophy\; mutations in the centromeric copy do not lead to disease. The centromeric copy may be a modifier of disease caused by mutation in the telomeric copy. The critical sequence difference between the two genes is a single nucleotide in exon 7, which is thought to be an exon splice enhancer. Note that the nine exons of both the telomeric and centromeric copies are designated historically as exon 1, 2a, 2b, and 3-8. It is thought that gene conversion events may involve the two genes, leading to varying copy numbers of each gene. The protein encoded by this gene localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein. Two transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with SMN1

  • survival motor neuron protein (LOC461829) antibody
  • survival of motor neuron 1, telomeric (Smn1) antibody
  • survival of motor neuron 1, telomeric (SMN1) antibody
  • survival motor neuron 1 (Smn1) antibody
  • survival motor neuron (SMN) antibody
  • survival motor neuron protein (LOC100713418) antibody
  • survival motor neuron protein (LOC100065744) antibody
  • survival motor neuron protein (LOC102176643) antibody
  • survival of motor neuron 1, telomeric (smn1) antibody
  • AI849087 antibody
  • BCD541 antibody
  • fa12d01 antibody
  • Gemin1 antibody
  • QtsA-10002 antibody
  • SMA antibody
  • SMA1 antibody
  • SMA2 antibody
  • SMA3 antibody
  • SMA4 antibody
  • SMA@ antibody
  • smn antibody
  • SMN1 antibody
  • SMN2 antibody
  • SMNT antibody
  • T-BCD541 antibody
  • TDRD16A antibody
  • wu:fa12d01 antibody

Protein level used designations for SMN1

survival of motor neuron 2, centromeric , survival motor neuron 1 , survival motor neuron protein , component of gems 1 , gemin-1 , survival motor neuron 1 protein , tudor domain containing 16A , survival of motor neuron protein , survival of motor neuron 1, telomeric , survival motor neuron protein 1

GENE ID SPECIES
461829 Pan troglodytes
64301 Rattus norvegicus
677703 Macaca mulatta
100170853 Sus scrofa
100171813 Pongo abelii
6606 Homo sapiens
20595 Mus musculus
493923 Felis catus
100713418 Cavia porcellus
100065744 Equus caballus
102176643 Capra hircus
102130507 Macaca fascicularis
30432 Danio rerio