Browse our anti-SRSF1 (SRSF1) Antibodies

Full name:: anti-serine/arginine-Rich Splicing Factor 1 Antibodies (SRSF1)

On www.antibodies-online.com are 69 serine/arginine-Rich Splicing Factor 1 (SRSF1) Antibodies from 20 different suppliers available. Additionally we are shipping SRSF1 Proteins (14) and SRSF1 Kits (11) and many more products for this protein. A total of 101 SRSF1 products are currently listed.

Synonyms:: 1110054N12Rik, 5730507C05Rik, 6330415C05Rik, AI482334, asf, AW491331, DKFZp469K2419, sf2, sf2p33, sfrs1, sfrs1b, srp30a, wu:fb80g05, zgc:65898, zgc:76897, zgc:111894

list all antibodies	Gene Name	GeneID	UniProt
	SRSF1	6426	Q07955
	SRSF1	110809	Q6PDM2
	SRSF1	689890
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Top referenced anti-SRSF1 Antibodies

Human Polyclonal SRSF1 Primary Antibody for ICC, IF - ABIN4353084 : Brown, Dobrikov, Gromeier et al.: Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated ... in Journal of virology 2014 (PubMed)
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Cow (Bovine) Polyclonal SRSF1 Primary Antibody for IHC, WB - ABIN2779013 : Velazquez-Dones, Hagopian, Ma, Zhong, Zhou, Ghosh, Fu, Adams: Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. in The Journal of biological chemistry 2005 (PubMed)
Show all 2 Pubmed References

More Antibodies against SRSF1 Interaction Partners

Human serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

We now show that the ability of SRPK1 (show SRPK1 Antibodies) to mobilize SRSF1 from speckles to the nucleoplasm is dependent on active CLK1 (show CDK11B Antibodies). Diffusion from speckles is promoted by the formation of an SRPK1 (show SRPK1 Antibodies)-CLK1 (show CDK11B Antibodies) complex that facilitates dissociation of SRSF1 from CLK1 (show CDK11B Antibodies) and enhances the phosphorylation of several serine-proline dipeptides in this SR protein (show RNPS1 Antibodies)
Authors showed that Mir505-3p was capable of inhibiting tumor proliferation driven by SRSF1 in two neural tumor cell lines, Neuro-2a (N2a) and U251, exclusively in serum-reduced condition. Authors observed that the protein level of SRSF1 was gradually promoted by increasing concentration of serum.
The present study suggested that the tumor suppressor miR30c may be involved in prostate cancer tumorigenesis, possibly via targeting ASF/SF2.
It has been proposed that SF2/ASF has a protective role against JC virus reactivation in multiple sclerosis patients.
Immune suppression of JC virus gene expression is mediated by SRSF1.
ASF/SF2 is identified as a splicing regulator (show PTBP2 Antibodies) of cyclin T1 (show CCNT1 Antibodies), which contributes to the control of the subsequent transcription events.
Findings suggest MALAT1 increases AKAP-9 (show AKAP9 Antibodies) expression by promoting SRPK1 (show SRPK1 Antibodies)-catalyzed SRSF1 phosphorylation in CRC (show CALR Antibodies) cells. These results reveal a novel molecular mechanism by which MALAT1 regulates AKAP-9 (show AKAP9 Antibodies) expression in CRC (show CALR Antibodies) cells.
high level of SF2, as a novel oncoprotein in RCC (show XRCC1 Antibodies), was significantly associated with poor survival in a large cohort of RCC (show XRCC1 Antibodies) specimens. Taken together, our study presents a road map for the prediction and validation of miR (show MLXIP Antibodies)-766-3p/SF2 axis and thus imparts a therapeutic way for further RCC (show XRCC1 Antibodies) progression.
The authors found that RNA recognition motif 1 (RRM1) in SRSF1 binds PP1 and represses its catalytic function through an allosteric mechanism.
We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 (show A2BP1 Antibodies) and SRSF1 complexes.The simulations predict unanticipated specific participation of Arg142 at the protein-RNA interface of the SRFS1 complex, which is subsequently confirmed by NMR and ITC measurements

Mouse (Murine) serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

In addition, overexpression of SRSF1 in XRCC4 (show XRCC4 Antibodies)-deficient cells restored the normal level of apoptosis, suggesting that SRSF1 functions downstream of XRCC4 (show XRCC4 Antibodies) in activating CAD (show CAD Antibodies).
SRSF1 is a key regulator of DBF4B (show DBF4 Antibodies) pre-mRNA splicing dysregulation in colon cancer. SRSF1 is required for cancer cell proliferation.
LncRNA MALAT1 is dysregulated in diabetic nephropathy and involved in high glucose-induced podocyte injury via its interplay with beta-catenin (show CTNNB1 Antibodies) and SRSF1.
Authors showed that Mir505-3p was capable of inhibiting tumor proliferation driven by SRSF1 in two neural tumor cell lines, Neuro-2a (N2a) and U251, exclusively in serum-reduced condition. Authors observed that the protein level of SRSF1 was gradually promoted by increasing concentration of serum.
This study showed that the splicing factor (show SLU7 Antibodies) kinase SRPK1 (show SRPK1 Antibodies) is a key regulator of spinal nociceptive processing in naive and nerve injured animals. We present evidence for a novel mechanism in which altered SRSF1 localization/function in neuropathic pain results in sensitization of spinal cord neurons.
The expression levels of three splicing factors, ESRP1 (show ESRP1 Antibodies), PTB (show PTBP1 Antibodies) and SF2/ASF, are significantly altered during cardiac hypertrophy in mice.
RRP1B suppresses metastatic progression by altering the transcriptome through its interaction with splicing regulators such as SRSF1
Deletion of RRM1 (show RRM1 Antibodies) eliminated the splicing activity of SRSF1 and thus cellular transformation.
Specific effects on regulated splicing by SR proteins SRSF1 and SRSF2 (show SRSF2 Antibodies) depends on a complex set of relationships with multiple other SR proteins in mammalian genomes.
Treatment with IL-17 (show IL17A Antibodies) prolongs the half-life of chemokine (show CCL1 Antibodies) CXCL1 (show CXCL1 Antibodies) mRNA via the adaptor TRAF5 (show TRAF5 Antibodies) and the splicing-regulatory factor SF2 (ASF).

SRSF1 Antigen Profile

Antigen Summary

This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13.

Alternative names and synonyms associated with SRSF1

serine and arginine rich splicing factor 1 (SRSF1) antibody
serine/arginine-rich splicing factor 1 (Srsf1) antibody
serine and arginine rich splicing factor 1 (Srsf1) antibody
serine/arginine-rich splicing factor 1b (srsf1b) antibody
serine/arginine-rich splicing factor 1 L homeolog (srsf1.L) antibody

1110054N12Rik antibody
5730507C05Rik antibody
6330415C05Rik antibody
AI482334 antibody
asf antibody
AW491331 antibody
DKFZp469K2419 antibody
sf2 antibody
sf2p33 antibody
sfrs1 antibody
sfrs1b antibody
srp30a antibody
wu:fb80g05 antibody
zgc:65898 antibody
zgc:76897 antibody
zgc:111894 antibody

Protein level used designations for SRSF1

ASF-1 , SR splicing factor 1 , alternative-splicing factor 1 , pre-mRNA-splicing factor SF2, P33 subunit , splicing factor 2 , splicing factor, arginine/serine-rich 1 , ASF/SF2 , pre-mRNA-splicing factor SRp30a , splicing factor, arginine/serine-rich 1 (ASF/SF2) , splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) , splicing factor, arginine/serine-rich 1B , splicing factor arginine/serine-rich 1 , serine/arginine-rich splicing factor 1B , splicing factor, arginine/serine-rich 1b

GENE ID	SPECIES
6426	Homo sapiens
110809	Mus musculus
609693	Canis lupus familiaris
615796	Bos taurus
654327	Sus scrofa
689890	Rattus norvegicus
772264	Gallus gallus
100173318	Pongo abelii
393565	Danio rerio
399226	Xenopus laevis

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Show all anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) Antibodies with Pubmed References

Human serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

Mouse (Murine) serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

Antigen Summary

Alternative names and synonyms associated with SRSF1

Protein level used designations for SRSF1