Browse our IMPDH2 Proteins (IMPDH2)

Full name:: IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 Proteins (IMPDH2)

On www.antibodies-online.com are 13 IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) Proteins from 8 different suppliers available. Additionally we are shipping IMPDH2 Antibodies (84) and IMPDH2 Kits (9) and many more products for this protein. A total of 117 IMPDH2 products are currently listed.

Synonyms:: cb635, imp2, IMPD, IMPD 2, IMPD2, IMPDH-II, impdh2, IMPDH 2, wu:fb64g02, wu:fc43f09

list all proteins	Gene Name	GeneID	UniProt
	IMPDH2	3615	P12268
	IMPDH2	301005
	IMPDH2	23918	P24547
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IMPDH2 Proteins (IMPDH2) by Origin

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Relevant Pathways for IMPDH2 Proteins

Ribonucleoside Biosynthetic Process

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Human IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) interaction partners

inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) is an intracellular target of the PPIA (show PPIA Proteins)-Sanglifehrin A binary complex.
The findings suggest that overexpressed IMPDH2 can be used as a biomarker for kidney and bladder cancer diagnosis and is a potential therapeutic target for the diseases
IMPDH2 is directly involved in the development of chemoresistance and radioresistance in osteosarcoma cells.
Compared with non-cancerous prostate tissues, IMPDH2 mRNA and protein expression levels were both significantly upregulated in prostate cancer tissues.
the localization of IMPDH2 inside the nucleus of human cells as well as the ultrastructure of R&R inclusions
Rods and rings (RR) are protein assemblies composed of CTPS1 and IMPDH2. Glutamine deprivation initiates reversible assembly of mammalian rods and rings.
Anti-IMPDH2 may cause difficulties in interpretation of immunofluorescence patterns in routine autoantibody testing.
IMPDHII plays an important role in the negative regulation of TLR2 signaling by modulating PI3K (show PIK3CA Proteins) activity.
in the absence of ligand the mobilities of "flap (show ALOX5AP Proteins)" and "loop" regions of IMPDH-II (1B3O) structures are mostly controlled by the four (W 1, W 2, W 3, and W 4) conserved water molecular centers and their dynamics
resequenced IMPDH1 and IMPDH2 using DNA from 288 individuals from three ethnic groups and performed functional genomic studies of the sequence variants observed; identfied 25 SNPs, 24 novel, in IMPDH2

Mouse (Murine) IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) interaction partners

IMPDH2 mediated guanine nucleotide synthesis is essential for normal development of the enteric nervous system and other neural crest derivatives.

IMPDH2 Protein Profile

Protein Summary

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Alternative names and synonyms associated with IMPDH2

inosine monophosphate dehydrogenase 2 (IMPDH2)
IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2.S)
IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2)
inosine monophosphate dehydrogenase 2 (impdh2)
inosine monophosphate dehydrogenase 2 (Impdh2)
inosine 5'-phosphate dehydrogenase 2 (impdh2)

cb635 protein
imp2 protein
IMPD protein
IMPD 2 protein
IMPD2 protein
IMPDH-II protein
impdh2 protein
IMPDH 2 protein
wu:fb64g02 protein
wu:fc43f09 protein

Protein level used designations for IMPDH2

IMP (inosine monophosphate) dehydrogenase 2 , inosine monophosphate dehydrogenase 2 , IMP (inosine 5'-monophosphate) dehydrogenase 2 , hCG2002013-like , inosine-5'-monophosphate dehydrogenase 2-like , IMP oxireductase 2 , IMPD 2 , IMPDH 2 , inosine 5' phosphate dehydrogenase 2 , inosine monophosphate dehydrogenase type II , inosine-5'-monophosphate dehydrogenase 2 , IMP dehydrogenase 2 , IMPDH-II , inosine 5'-phosphate dehydrogenase 2 , inosine 5-monophosphate dehydrogenase 2 , IMP dehydrogenase type II

GENE ID	SPECIES
100063255	Equus caballus
398453	Xenopus laevis
460362	Pan troglodytes
493428	Xenopus (Silurana) tropicalis
708307	Macaca mulatta
100020776	Monodelphis domestica
100196657	Salmo salar
100220774	Taeniopygia guttata
100355621	Oryctolagus cuniculus
100387794	Callithrix jacchus
100443958	Pongo abelii
100478982	Ailuropoda melanoleuca
100561879	Anolis carolinensis
3615	Homo sapiens
416058	Gallus gallus
476630	Canis lupus familiaris
511969	Bos taurus
301005	Rattus norvegicus
317745	Danio rerio
399236	Xenopus laevis
23918	Mus musculus

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