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This study demonistrated that use joint test to identified that UPP2 association to Autism Spectrum Disorder.
A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity
identification of the novel human uridine phosphorylase, UDPase 2, with broad substrate specificity; UPase-2 gene was mapped to chromosome 2q24.1 and the 2.2-kb mRNA was predominantly expressed in kidney
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
uridine phosphorylase, like
, uridine phosphorylase 2
, UPase 2
, liver-specific uridine phosphorylase
, urdPase 2
, uridine phosphorylase-2