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Full name:: anti-Apoptosis-Associated tyrosine Kinase Antibodies (AATK)

On www.antibodies-online.com are 57 Apoptosis-Associated tyrosine Kinase (AATK) Antibodies from 15 different suppliers available. Additionally we are shipping AATK Kits (18) and AATK Proteins (7) and many more products for this protein. A total of 86 AATK products are currently listed.

Synonyms:: AATYK, aatyk1, LMR1, LMTK1, mKIAA0641, p35BP

list all antibodies	Gene Name	GeneID	UniProt
	AATK	9625	Q6ZMQ8
	AATK	11302	Q80YE4
	AATK	690853
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Human Apoptosis-Associated tyrosine Kinase (AATK) interaction partners

ATKK was validated as a target gene of miR (show MLXIP Antibodies)-558, and upregulation of miR (show MLXIP Antibodies)-558 was observed in radioresistant lung cancer cells. Additionally, ectopic overexpression of ATKK partially but significantly reduced the miR (show MLXIP Antibodies)-558-induced radioresistance.
Apoptosis-associated tyrosine kinase is a Cdk5 (show CDK5 Antibodies) activator p35 binding protein.

Mouse (Murine) Apoptosis-Associated tyrosine Kinase (AATK) interaction partners

LMTK1 negatively controls dendritic formation by regulating Rab11A (show RAB11A Antibodies)-positive endosomal trafficking.
Overexpression of the unphosphorylated mutant LMTK1-S34A dramatically promotes axonal outgrowth in cultured neurons.
results suggest a possibility that AATYK1A plays a role in early to recycling endosomes and its function is regulated by phosphorylation with Cdk5 (show CDK5 Antibodies) or Src (show SRC Antibodies)-family kinases
Expression of AATYK mRNA and protein increased during postnatal brain development. In immature granule cells, overexpression of AATYK promoted neurite outgrowth; a tyrosine kinase (show TYRO3 Antibodies)-defective mutant significantly inhibited it.
phosphorylation states of AATYK are closely related to the high potassium-induced survival and low potassium-induced apoptosis of cerebellar granule cells
AATYK1 indirectly inhibits the SPAK (show STK39 Antibodies)/WNK4 (show WNK4 Antibodies) activation of the Na-K-2Cl cotransporter (show SLC12A1 Antibodies) by scaffolding an inhibitory phosphatase in proximity to a stimulatory kinase.

AATK Antigen Profile

Antigen Summary

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with AATK

apoptosis associated tyrosine kinase (AATK) antibody
apoptosis-associated tyrosine kinase (Aatk) antibody
apoptosis associated tyrosine kinase (Aatk) antibody
serine/threonine-protein kinase LMTK1 (LOC101101878) antibody

AATYK antibody
aatyk1 antibody
LMR1 antibody
LMTK1 antibody
mKIAA0641 antibody
p35BP antibody

Protein level used designations for AATK

CDK5-binding protein , brain apoptosis-associated tyrosine kinase , lemur tyrosine kinase 1 , p35-binding protein , serine/threonine-protein kinase LMTK1 , apoptosis-associated tyrosine kinase 1B

GENE ID	SPECIES
9625	Homo sapiens
11302	Mus musculus
690853	Rattus norvegicus
100734696	Cavia porcellus
100627757	Sus scrofa
483358	Canis lupus familiaris
511515	Bos taurus
422076	Gallus gallus
101101878	Ovis aries

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