Browse our anti-ARPC1B (ARPC1B) Antibodies

Full name:: anti-Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa Antibodies (ARPC1B)

On www.antibodies-online.com are 65 Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B) Antibodies from 0 different suppliers available. A total of 88 ARPC1B products are currently listed.

Synonyms:: 41kDa, AA408064, AA408534, AA571392, ACTIN-RELATED PROTEIN C1, actin-related protein C1B, AF007010, arc41, ARP2, ARPC1, arpc1a, AW208418, cb871, F16D14.14, F16D14_14, fj15h02, L72, p40-arc, p41-arc, SOP2Hs, wu:fj08e12, wu:fj15h02, zgc:64056

list all antibodies	Gene Name	GeneID	UniProt
Anti-Human ARPC1B	ARPC1B	10095	O15143
Anti-Rat ARPC1B	ARPC1B	54227	O88656
Anti-Mouse ARPC1B	ARPC1B	11867	Q9WV32
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Relevant Pathways for anti-ARPC1B Antibodies

More product categories related to ARPC1B Antibody

Top referenced anti-ARPC1B Antibodies

Human Polyclonal ARPC1B Primary Antibody for ELISA, WB - ABIN268667 : Moghe, Jiang, Miura, Cerny, Tsai, Furukawa: The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A. in Biology open 2012 (PubMed)
Show all 3 Pubmed References
Human Polyclonal ARPC1B Primary Antibody for IHC, IHC (p) - ABIN4278119 : Abella, Galloni, Pernier, Barry, Kjær, Carlier, Way: Isoform diversity in the Arp2/3 complex determines actin filament dynamics. in Nature cell biology 2015 (PubMed)
Show all 2 Pubmed References

More Antibodies against ARPC1B Interaction Partners

Human Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B) interaction partners

A homozygous frameshift mutation in ARPC1B (p.Val91Trpfs*30) was identified in a child with microthrombocytopenia, eosinophilia and inflammatory disease. Platelet lysates contained no ARPC1B protein and reduced Arp2 (show ACTR2 Antibodies)/3 complex. Missense ARPC1B mutations were identified in an unrelated patient with similar symptoms and ARPC1B deficiency. ARPC1B-deficient platelets are microthrombocytes with abnormal spreading behavior.
A homozygous 2 bp deletion, n.c.G623DEL-TC (p.V208VfsX20), in Arp2 (show ACTR2 Antibodies)/3 complex component ARPC1B that causes a frame shift resulting in premature termination was found in 2 brothers with hematopoietic and immunologic symptoms reminiscent of Wiskott-Aldrich syndrome. Wild-type ARPC1B but not mutant was able to rescue a deficiency in a zebrafish model. ARPC1B expression is restricted to hematopoietic cells.
This study identified two low-frequency nonsynonymous variants at FKBPL (show FKBPL Antibodies) (rs200847762, OR = 0.34, 95% CI = 0.20-0.57, P = 4.31 x 10-5) and ARPC1B (rs1045012, OR = 0.56, 95% CI = 0.43-0.74, P = 4.30 x 10-5) associated with breast cancer risk.
low-expression of ARPC1B is significantly associated with LNM and advanced tumor staging whereas high expression of Cav-1 (show CAV1 Antibodies) can be a prognostic indicator for poor prognosis in OSCC patients.
p41-Arc activates a senescence program in p53 (show TP53 Antibodies)- and Rb-independent ways.
Arpc1b is both a physiological activator and substrate of Aurora A kinase (show AURKA Antibodies) and these interactions help to maintain mitotic integrity in mammalian cells.
INSIG1 (show INSIG1 Antibodies) and p41 (show EPB41 Antibodies) Arp2 (show ACTR2 Antibodies)/3 complex (p41-Arc)reduced expression might be involved in gastric cancer development or progression
Phosphorylation of p41-ARC by p21-activated kinase 1 (show PAK1 Antibodies).
From the analysis of the different radio-sensitivity cancer cell lines, the Arpc1b gene was selected as a prediction marker gene for sensitivity of CMM to radiotherapy.

Cow (Bovine) Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B) interaction partners

crystal structure of Arp2 (show ACTR2 Antibodies)/3 complex
These results demonstrate an important role for CRMP-1 (show CRMP1 Antibodies) in Listeria actin comet tail formation and open the possibility that CRMP-1 (show CRMP1 Antibodies) controls cell motility by modulating Arp2 (show ACTR2 Antibodies)/3 activation.
The GMF-Arp2 interface reveals how the ADF-H actin-binding domain in GMF is exploited to specifically recognize Arp2/3 complex and not actin.
interacts with contactin and N-WASp
Data show that L. monocytogenes motility can be separated into an Arp2 (show ACTR2 Antibodies)/3-dependent nucleation phase, and an Arp2 (show ACTR2 Antibodies)/3-independent elongation phase which is dependent upon fascin (show FSCN1 Antibodies).
crystal structures of Arp2/3 complex with bound ATP or ADP
WASp stabilizes p35-dependent closure of the complex, holding Arp2 and Arp3 closer together to nucleate an actin filament.
domain rearrangements of Arp2 and Arp3 result in a closed conformational state consistent with an "actin-dimer" model for the active state

ARPC1B Antigen Profile

Antigen Summary

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Alternative names and synonyms associated with ARPC1B

actin related protein 2/3 complex subunit 1B (ARPC1B) antibody
ARP2 actin related protein 2 homolog (ACTR2) antibody
actin related protein 2/3 complex, subunit 1B (Arpc1b) antibody
ARP2/3 complex 41 kDa subunit (EHI_094120) antibody
actin related protein 2/3 complex, subunit 1B (arpc1b) antibody
actin-related protein C1B (ARPC1B) antibody
actin-related protein 2/3 complex subunit 1B (LOC100410640) antibody
actin related protein 2/3 complex subunit 1B S homeolog (arpc1b.S) antibody
actin related protein 2/3 complex subunit 1B (Arpc1b) antibody

41kDa antibody
AA408064 antibody
AA408534 antibody
AA571392 antibody
ACTIN-RELATED PROTEIN C1 antibody
actin-related protein C1B antibody
AF007010 antibody
arc41 antibody
ARP2 antibody
ARPC1 antibody
arpc1a antibody
AW208418 antibody
cb871 antibody
F16D14.14 antibody
F16D14_14 antibody
fj15h02 antibody
L72 antibody
p40-arc antibody
p41-arc antibody
SOP2Hs antibody
wu:fj08e12 antibody
wu:fj15h02 antibody
zgc:64056 antibody

Protein level used designations for ARPC1B

ARP2/3 protein complex subunit p41 , actin-related protein 2/3 complex subunit 1B , arp2/3 complex 41 kDa subunit , actin-like protein 2 , actin-related protein 2 , Actin-related protein complex 1b , p41-ARC , actin related protein 2/3 complex subunit 1B , ARP2/3 complex 41 kDa subunit , actin related protein 2/3 complex, subunit 1A, 41kDa , actin related protein 2/3 complex, subunit 1B, 41kDa , actin-related protein 2/3 complex subunit 1B-like

GENE ID	SPECIES
10095	Homo sapiens
538486	Bos taurus
54227	Rattus norvegicus
326600	Bos taurus
3403334	Entamoeba histolytica HM-1:IMSS
335474	Danio rerio
11867	Mus musculus
416490	Gallus gallus
463568	Pan troglodytes
479744	Canis lupus familiaris
718668	Macaca mulatta
817687	Arabidopsis thaliana
100059292	Equus caballus
100174964	Sus scrofa
100346759	Oryctolagus cuniculus
100410640	Callithrix jacchus
100458060	Pongo abelii
100483279	Ailuropoda melanoleuca
444264	Xenopus laevis
100723268	Cavia porcellus

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Show all anti-Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B) Antibodies with Pubmed References

Human Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B) interaction partners

Cow (Bovine) Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B) interaction partners

Antigen Summary

Alternative names and synonyms associated with ARPC1B

Protein level used designations for ARPC1B