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anti-Human EPH Receptor A8 Antibodies:
anti-Mouse (Murine) EPH Receptor A8 Antibodies:
anti-Rat (Rattus) EPH Receptor A8 Antibodies:
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Human Monoclonal EPH Receptor A8 Primary Antibody for ELISA, WB - ABIN969105
Yamaguchi, Pasquale: Eph receptors in the adult brain. in Current opinion in neurobiology 2004
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Human Monoclonal EPH Receptor A8 Primary Antibody for ELISA, WB - ABIN966074
Gu, Shim, Shin, Kim, Park, Han, Park: The EphA8 receptor induces sustained MAP kinase activation to promote neurite outgrowth in neuronal cells. in Oncogene 2005
Show all 2 Pubmed References
Q-PCR and IHC staining revealed that EphA8 was highly expressed in OTSCC tissues, especially in advanced stage OTSCC tissues. Kaplan-Meier curve showed that high EphA8 expression was significantly associated with poor prognosis.
Gene-based analysis identified EPHA6 as the gene most significantly associated with paclitaxel-induced neuropathy...This first study sequencing EPHA genes revealed that low-frequency variants in EPHA6, EPHA5, and EPHA8 contribute to the susceptibility to paclitaxel-induced neuropathy
High EPHA8 expression is associated with epithelial ovarian cancer.
Human miR-10a and EphA8 regulate epithelial-mesenchymal transition (EMT) to affect glioma cell migration and invasion.
RINL, as a GEF for Rab5 subfamily, is implicated in the EphA8-degradation pathway via its interaction with odin.
role in stimulated cell migration in presnce of p110 gamma PI-3 kinase
EphA8 receptor is capable of inducing a sustained increase in MAPK activity, thereby promoting neurite outgrowth in neuronal cells
Data suggest that Odin levels play a critical role in regulating the stability of EphA2 and A8 in response to ligand stimulation and by modulating the ubiquitination process.
1-kb enhancer region, directs expression in the embryo to the anterior region of the developing midbrain.
Regulation of EphA8 gene expression is accomplished by TALE homeobox transcription factors during development of the mesencephalon.
These findings support a possible function for Anks family proteins as scaffolding proteins of the EphA8 signaling pathway.
This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
EPH receptor A8
, protein-tyrosine kinase (E17)
, ephrin receptor EphA8-like
, ephrin type-A receptor 8-like
, EPH- and ELK-related kinase
, EPH- and ELK-related tyrosine kinase
, EPH-like kinase 3
, ephrin type-A receptor 8
, hydroxyaryl-protein kinase
, protein-tyrosine kinase
, tyrosine-protein kinase receptor EEK
, tyrosylprotein kinase
, Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) (EPH-and ELK-related kinase)