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anti-Human EPH Receptor B2 Antibodies:
anti-Mouse (Murine) EPH Receptor B2 Antibodies:
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Human Polyclonal EPH Receptor B2 Primary Antibody for CyTOF, FACS - ABIN4900040
Boyer-Di Ponio, El-Ayoubi, Glacial, Ganeshamoorthy, Driancourt, Godet, Perrière, Guillevic, Couraud, Uzan: Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes. in PLoS ONE 2014
Show all 26 Pubmed References
Human Monoclonal EPH Receptor B2 Primary Antibody for IHC (fro), FACS - ABIN2689499
Foster, Gordon, Cardenas, Veiga-Fernandes, Makinen, Grigorieva, Wilkinson, Blackburn, Richie, Manley, Adams, Kioussis, Coles: EphB-ephrin-B2 interactions are required for thymus migration during organogenesis. in Proceedings of the National Academy of Sciences of the United States of America 2010
Show all 4 Pubmed References
Human Monoclonal EPH Receptor B2 Primary Antibody for ICC, ELISA - ABIN1724695
Huusko, Ponciano-Jackson, Wolf, Kiefer, Azorsa, Tuzmen, Weaver, Robbins, Moses, Allinen, Hautaniemi, Chen, Elkahloun, Basik, Bova, Bubendorf, Lugli, Sauter, Schleutker, Ozcelik, Elowe, Pawson, Trent et al.: Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. ... in Nature genetics 2004
Show all 2 Pubmed References
Human Polyclonal EPH Receptor B2 Primary Antibody for ELISA, WB - ABIN188674
Litterst, Georgakopoulos, Shioi, Ghersi, Wisniewski, Wang, Ludwig, Robakis: Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor. in The Journal of biological chemistry 2007
Show all 2 Pubmed References
Human Polyclonal EPH Receptor B2 Primary Antibody for IF (p), IHC (p) - ABIN730708
Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. in Nature communications 2016
Human Polyclonal EPH Receptor B2 Primary Antibody for IHC (p) - ABIN391919
Thanos, Goodwill, Bowie: Oligomeric structure of the human EphB2 receptor SAM domain. in Science (New York, N.Y.) 1999
Show all 4 Pubmed References
Human Monoclonal EPH Receptor B2 Primary Antibody for FACS - ABIN4897097
Francescangeli, Contavalli, De Angelis, Baiocchi, Gambara, Pagliuca, Fiorenzano, Prezioso, Boe, Todaro, Stassi, Castro, Watanabe, Salomon, De Maria, Minchiotti, Zeuner: Dynamic regulation of the cancer stem cell compartment by Cripto-1 in colorectal cancer. in Cell death and differentiation 2015
Human Monoclonal EPH Receptor B2 Primary Antibody for CyTOF, FACS - ABIN4900039
De Robertis, Loiacono, Fusilli, Poeta, Mazza, Sanchez, Marchionni, Signori, Lamorte, Vescovi, Garcia-Foncillas, Fazio: Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2016
These findings suggested that miR (show MLXIP Antibodies)-204 might serve as a tumor suppressor in the development of cervical cancer by directly targeting EphB2.
EphB2 signaling-mediated Sirt3 (show SIRT3 Antibodies) expression reduces MSC (show MSC Antibodies) senescence by maintaining mitochondrial reactive oxygen species homeostasis.
This study showed that EphB2 cells have a transient increase in migration after heterotypic activation, which underlies a shift in the EphB2-ephrinB1 (show EFNB1 Antibodies) border but is not required for segregation or border sharpening.
This is the first study to link SLC1A3 (show SLC1A3 Antibodies) and EPHB2 to clinically relevant vertebral osteoporosis phenotypes.
Data show that EPHB2 predicted poor breast cancer survival and EPHB2 protein expression has also prognostic value depending on cell localization.
showed that patients with SSc (show CYP11A1 Antibodies) or SLE have AAb against EphB2, a protein involved in angiogenesis, and THEX1 (show ERI1 Antibodies), a 3'-5' exoribonuclease involved in histone mRNA degradation. We have further identified a peptide from EphB2 as a specific and sensitive tool for SLE diagnosis
show that expression of EPHB2 and SNAIL1 (show SNAI1 Antibodies) - an inducer of epithelial-mesenchymal transition (EMT (show ITK Antibodies)) - is anti-correlated in colorectal cancer cell lines and tumors
Tiam2 (show TIAM2 Antibodies)/Rac (show AKT1 Antibodies) are key components of EphB2 trans-endocytosis and are important for cell repulsion.
High expression of junctional adhesion molecule-A (show F11R Antibodies) and EphB2 can predict poor overall survival and high mortality rate, and EphB2 is an independent prognostic biomarker in lung adenocarcinoma patients.
Data show that activation of EphB2 receptor kinase arrests tau protein hyperphosphorylation through phosphatidylinositol 3-kinase (PI3K)/Akt protein-mediated glycogen synthase kinase-3beta (GSK-3beta) inhibition.
although both EphB2 and EphB3 (show EPHB3 Antibodies) are necessary for cortical thymic epithelial maturation, the relevance of EphB3 (show EPHB3 Antibodies) is greater since EphB3 (show EPHB3 Antibodies)-/- thymic cortex exhibits a more severe phenotype than that of EphB2-deficient thymuses
ephrin-B2 (show EFNB2 Antibodies) and EphA4 (show EPHA4 Antibodies) have graded and modular expression patterns in the developing inferior colliculus
Overexpression of EphB2 also rescued the ADDLs-induced depletion of the expression of EphB2 and GluN2B (show GRIN2B Antibodies)-containing NMDA receptors trafficking in cultured hippocampal neurons.
ephrin B3 (show EFNB3 Antibodies)/EphB2 are obvious candidates for driving the Syk (show SYK Antibodies)-dependent repulsive response.
The results of this study indicated that the decrease in spine density in the mPFC was associated with susceptibility to stress, and EphB2 downregulation in the mPFC increased the vulnerability to stress.
We here identify that EphB2 receptor tyrosine kinase (show ERBB3 Antibodies), which is specifically expressed in glutamatergic neurons, is required for the innate fear responses in the neonatal brain.
Here, we identified the interaction sites of the EphB2 FN domain with ADDLs for the first time to develop a small (10 aa) peptide (Pep63) capable of blocking the EphB2-ADDL (show ADD3 Antibodies) interaction.
EphB4 (show EPHB4 Antibodies) plays an irreplaceable role in bone regeneration in an inflammatory microenvironment, whereas the functional loss of ephrinB2 (show EFNB2 Antibodies) can be effectively compensated, most possibly by other ephrins with similar chemical structures
Authors suggest that aging is accompanied by the upregulation of miR-204 in the hippocampus, which downregulates EphB2 and results in reduced surface and total NR1 expression.
Findings suggest that a combination of forward and reverse EphB1 (show EPHB1 Antibodies)/2 receptor-mediated signaling contribute to posterior branch of the anterior commissure and corpus callosum axon guidance
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
ephrin receptor EphB2
, EPH receptor B2
, ephrin type-B receptor 2-like
, EPH-like kinase 5
, developmentally-regulated Eph-related tyrosine kinase
, elk-related tyrosine kinase
, eph tyrosine kinase 3
, ephrin type-B receptor 2
, protein-tyrosine kinase HEK5
, renal carcinoma antigen NY-REN-47
, tyrosine-protein kinase TYRO5
, tyrosine-protein kinase receptor EPH-3
, neural kinase
, nuk receptor tyrosine kinase
, tyrosine-protein kinase receptor SEK-3
, embryo kinase 5 protein CEK5