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EPH Receptor B2 Products

(EPH Receptor B2 (EPHB2))
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008].

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Featured EPH Receptor B2 Categories

EPH Receptor B2 Antibodies

High quality antibodies with extensive validation data.

EPH Receptor B2 ELISA Kits

Reliable ELISA kits for a wide range of species.

EPH Receptor B2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EPH Receptor B2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (4)
Cat. No. ABIN391920
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN3030824
Quantity 0.2 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IHC (fro), IF (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN730708
Quantity 100 μL
Datasheet Datasheet

Recommended EPH Receptor B2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
Cat. No. ABIN1981718
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966540
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381113
Quantity 96 tests
Datasheet Datasheet

Recommended EPH Receptor B2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274553
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274547
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274560
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our EPH Receptor B2 products

Ernst, Böhler, Hagenston, Hoffmann, Heiland, Sticht, Bendszus, Hecker, Bading, Marti, Korff, Kunze: "EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke." in: Acta neuropathologica communications, Vol. 7, Issue 1, pp. 15, (2019) (PubMed).

Mimche, Lee, Mimche, Thapa, Grakoui, Henkemeyer, Lamb: "EphB2 receptor tyrosine kinase promotes hepatic fibrogenesis in mice via activation of hepatic stellate cells." in: Scientific reports, Vol. 8, Issue 1, pp. 2532, (2018) (PubMed).

Yang, Chen, Zhang, Yang, Wang, Yuan: "EphrinB/EphB signaling contributes to spinal nociceptive processing via calpain‑1 and caspase‑3." in: Molecular medicine reports, Vol. 18, Issue 1, pp. 268-278, (2018) (PubMed).

Tüysüz, van Bloois, van den Brink, Begthel, Verstegen, Cruz, Hui, van der Laan, de Jonge, Vries, Braakman, Mastrobattista, Cornelissen, Clevers, Ten Berge: "Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells." in: Nature communications, Vol. 8, pp. 14578, (2017) (PubMed).

Liu, Tsai, Chen, Yang, Chang, Cheng, Turner, Yanagawa, Wang, Yu: "Ascl1 promotes tangential migration and confines migratory routes by induction of Ephb2 in the telencephalon." in: Scientific reports, Vol. 7, pp. 42895, (2017) (PubMed).

Miura, Suzuki: "Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming." in: Cell stem cell, Vol. 21, Issue 4, pp. 456-471.e5, (2017) (PubMed).

ONeill, Kindberg, Niethamer, Larson, Ho, Greenberg, Bush: "Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation." in: The Journal of cell biology, Vol. 215, Issue 2, pp. 217-229, (2017) (PubMed).

Shi, Sun, Hu, Liu, Hu, Sun, Yao, Sun, Hao, Wei, Han, Gao: "Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 36, Issue 47, pp. 11959-11973, (2017) (PubMed).

Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: "Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation." in: Nature communications, Vol. 7, pp. 10963, (2016) (PubMed).

De Robertis, Loiacono, Fusilli, Poeta, Mazza, Sanchez, Marchionni, Signori, Lamorte, Vescovi, Garcia-Foncillas, Fazio: "Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 1, pp. 159-170, (2016) (PubMed).

Synonyms and alternative names related to EPH Receptor B2

EPH receptor B2 (EPHB2), mitogen-activated protein kinase 1 (MAPK1), Eph receptor B2 (Ephb2), EPH receptor B2 L homeolog (ephb2.L), eph receptor B2a (ephb2a), eph receptor B2b (ephb2b), CAPB, Cek5, cek5, DRT, Drt, EK5, ephb2, EPHT3, ERK, Erk, ERK2, ERT1, ETECK, Hek5, MAPK2, Nuk, p38, p40, p41, p41mapk, P42MAPK, PCBC, PRKM1, PRKM2, Prkm5, Qek5, RGD1564232, Sek3, si:ch73-160e9.1, tpx2, Tyro5, wu:fb09e10, wu:fc64a03, wu:fi18g12, xEphB2, zgc:112296

Protein level used designations for EPH Receptor B2

  • EPH-like kinase 5
  • developmentally-regulated Eph-related tyrosine kinase
  • elk-related tyrosine kinase
  • eph tyrosine kinase 3
  • ephrin type-B receptor 2
  • protein-tyrosine kinase HEK5
  • renal carcinoma antigen NY-REN-47
  • tyrosine-protein kinase TYRO5
  • tyrosine-protein kinase receptor EPH-3
  • ERK-2
  • MAP kinase 1
  • MAP kinase 2
  • MAP kinase isoform p42
  • MAPK 2
  • extracellular signal-regulated kinase 2
  • mitogen-activated protein kinase 2
  • p42-MAPK
  • protein tyrosine kinase ERK2
  • EK5
  • cEK5
  • embryo kinase 5 protein CEK5
  • ephrin receptor EphB2
  • EPH receptor B2
  • ephrin type-B receptor 2-like
  • neural kinase
  • nuk receptor tyrosine kinase
  • tyrosine-protein kinase receptor SEK-3
  • EphB2-tyrosine kinase receptor
  • TPX2, microtubule-associated, homolog
  • eph receptor B2b
  • fi18g12
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