anti-Human Ephrin A1 antibody for Immunocytochemistry

Recommended Ephrin A1 Antibody

Antigen
Ephrin A1 (EFNA1) Antibodies
  • Xefrin-A1
  • b61
  • ecklg
  • efl1
  • efna1
  • efna1a
  • elfa-a
  • epha1
  • eplg1
  • lerk1
  • tnfaip4
  • xelf-a'
  • xelfa
  • AI325262
  • B61
  • Efl1
  • Epl1
  • Eplg1
  • Lerk1
  • ECKLG
  • EFL1
  • EPLG1
  • LERK-1
  • LERK1
  • TNFAIP4
  • efna1b
  • MGC130661
  • ephrin-A1 S homeolog
  • ephrin-A1
  • ephrin A1
  • ephrin-A1b
  • ephrin-A1 L homeolog
  • efna1.S
  • efna1
  • EFNA1
  • efna1b
  • Efna1
  • efna1.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
82
60
56
3
3
3
Host
Rabbit
82
15
4
1
Clonality
Polyclonal
Conjugate
This Ephrin A1 antibody is un-conjugated
6
5
5
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
62
50
28
13
12
10
5
4
3
1
1
1
Options

Available images

Catalog No. ABIN6261448
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
10 ABIN6257172 ELISA ICC IF WB Rabbit IgG Polyclonal 0
10 ABIN1867694 ICC IHC WB Rabbit IgG AA 19-182 Polyclonal 0
1 ABIN1864174 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG 0

General

Antigen Ephrin A1 (EFNA1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(82), (60), (56), (3), (3), (3)
Host Rabbit
(82), (15), (4), (1)
Clonality
Polyclonal
Conjugate This Ephrin A1 antibody is un-conjugated
(6), (5), (5), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(62), (50), (28), (13), (12), (10), (5), (4), (3), (1), (1), (1)
Supplier

Product Details anti-Ephrin A1 Antibody

Target Details Ephrin A1 Application Details Handling Images
Specificity EFNA1 Antibody detects endogenous levels of total EFNA1
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human EFNA1
Isotype IgG
Plasmids, Primers & others

Target Details Ephrin A1

Product Details anti-Ephrin A1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name EFNA1 (EFNA1 Antibody Abstract)
Background

Description: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.

Gene: EFNA1

Molecular Weight 24kDa
Gene ID 1942
UniProt P20827
Pathways RTK Signaling

Application Details

Product Details anti-Ephrin A1 Antibody Target Details Ephrin A1 Handling Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-Ephrin A1 Antibody Target Details Ephrin A1 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-Ephrin A1 Antibody Target Details Ephrin A1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Ephrin A1 (EFNA1) antibody (ABIN6261448) Western blot analysis of Hela whole cell lysates, using EFNA1 Antibody. The lane on t...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Ephrin A1 (EFNA1) antibody (ABIN6261448) ABIN6277528 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeab...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Ephrin A1 (EFNA1) antibody (ABIN6261448) ABIN6277528 staining 293 by IF/ICC. The sample were fixed with PFA and permeabilized ...
Immunohistochemistry (IHC) image for anti-Ephrin A1 (EFNA1) antibody (ABIN6261448) ABIN6277528 at 1/100 staining Mouse brain tissue by IHC-P. The sample was formaldehyd...