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anti-Human Galectin 3 Antibodies:
anti-Rat (Rattus) Galectin 3 Antibodies:
anti-Mouse (Murine) Galectin 3 Antibodies:
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Human Polyclonal Galectin 3 Primary Antibody for CyTOF, FACS - ABIN4899436
Thijssen, Hulsmans, Griffioen: The galectin profile of the endothelium: altered expression and localization in activated and tumor endothelial cells. in The American journal of pathology 2008
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Human Monoclonal Galectin 3 Primary Antibody for IHC (f), ICS - ABIN2689513
Cherayil, Weiner, Pillai: The Mac-2 antigen is a galactose-specific lectin that binds IgE. in The Journal of experimental medicine 1990
Show all 4 Pubmed References
Human Polyclonal Galectin 3 Primary Antibody for IF (p), IHC (p) - ABIN672321
Lee, Bae, Choi, Park, Chun: Molecular cloning and expression analysis of pig CD7. in Veterinary research communications 2014
Show all 2 Pubmed References
Human Monoclonal Galectin 3 Primary Antibody for ELISA, FACS - ABIN152697
Liu, Hsu, Zuberi, Hill, Shenhav, Kuwabara, Chen: Modulation of functional properties of galectin-3 by monoclonal antibodies binding to the non-lectin domains. in Biochemistry 1996
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Human Monoclonal Galectin 3 Primary Antibody for Func, IA - ABIN2192045
Sano, Hsu, Yu, Apgar, Kuwabara, Yamanaka, Hirashima, Liu: Human galectin-3 is a novel chemoattractant for monocytes and macrophages. in Journal of immunology (Baltimore, Md. : 1950) 2000
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Human Polyclonal Galectin 3 Primary Antibody for WB - ABIN517489
Shi, Tan, Meng, Yu, Li, Yin, Wei, Luo, Jia, Zhang, Wu, Mi, Wang: Association of anti-acidic ribosomal protein P0 and anti-galectin 3 antibodies with the development of skin lesions in systemic lupus erythematosus. in Arthritis & rheumatology (Hoboken, N.J.) 2014
Human Polyclonal Galectin 3 Primary Antibody for ELISA, WB - ABIN2473746
Dumic, Dabelic, Flögel: Galectin-3: an open-ended story. in Biochimica et biophysica acta 2006
Cow (Bovine) Polyclonal Galectin 3 Primary Antibody for IHC, WB - ABIN2785832
Bartolazzi, Orlandi, Saggiorato, Volante, Arecco, Rossetto, Palestini, Ghigo, Papotti, Bussolati, Martegani, Pantellini, Carpi, Giovagnoli, Monti, Toscano, Sciacchitano, Pennelli, Mian, Pelizzo, Rugge, Troncone, Palombini, Chiappetta, Botti, Vecchione, Be: Galectin-3-expression analysis in the surgical selection of follicular thyroid nodules with indeterminate fine-needle aspiration cytology: a prospective multicentre study. in The lancet oncology 2008
Show all 2 Pubmed References
Human Polyclonal Galectin 3 Primary Antibody for IHC (p), WB - ABIN657647
Salomonsson, Carlsson, Osla, Hendus-Altenburger, Kahl-Knutson, Oberg, Sundin, Nilsson, Nordberg-Karlsson, Nilsson, Karlsson, Rini, Leffler: Mutational tuning of galectin-3 specificity and biological function. in The Journal of biological chemistry 2010
Show all 4 Pubmed References
Mouse (Murine) Monoclonal Galectin 3 Primary Antibody for EIA, FACS - ABIN114277
Knisley, Weitlauf: Compartmentalized reactivity of M3/38 (anti-Mac-2) and M3/84 (anti-Mac-3) in the uterus of pregnant mice. in Journal of reproduction and fertility 1993
Show all 12 Pubmed References
Demonstrate that galectin-3 plays a critical role in hensin (show DMBT1 Antibodies) ECM (show MMRN1 Antibodies) assembly by oligomerizing secreted monomeric hensin (show DMBT1 Antibodies).
NRG1 (show NRG1 Antibodies) and Gal-3 were significantly more elevated in cancer patients than in healthy controls.
GAL3 activates pancreatic stellate cells to produce inflammatory cytokines via ITGB1signaling to ILK (show ILK Antibodies) and activation of NF-kappaB (show NFKB1 Antibodies) in pancreatic tumors.
discovery of site specific N-glycosylation changes of LGALS3BP in association of PDAC may provide useful clues to facilitate cancer detection or phenotype stratification
Our findings establish gal-3 as a molecular regulator of the JAG1 (show JAG1 Antibodies)/Notch-1 (show NOTCH1 Antibodies) signaling pathway and have direct implications for the development of strategies aimed at controlling tumor angiogenesis.
findings reveal that differential levels of Gal-3 and Gal-8 expression and recruitment to Group A streptococcus (GAS) between epithelial cells and endothelial cells may contribute to the different outcomes of GAS elimination or survival and growth of GAS in these two types of cells.
The methylation frequency of the galectin-3 promoter was significantly higher while galectin-3 mRNA was lower in acute-on-chronic hepatitis B liver failure (ACHBLF) than in chronic hepatitis B and healthy controls. The results suggest that hypermethylation of the galectin-3 promoter might be an early biomarker for predicting disease severity and prognosis in patients with ACHBLF.
Serum Gal-3 and Nox4 (show NOX4 Antibodies) levels were significantly elevated and correlated in 26 human pulmonary arterial hypertension patients when compared with 14 age- and sex-matched healthy controls.
Gal-3 staining in the nucleus could be a new positive prognosticator for ovarian cancer.
These results demonstrate Tsc2 (show TSC2 Antibodies)-deficient mesenchymal progenitors cause aberrant morphogenic signals, and identify an expression signature including Lgals3 relevant for human disease of TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) inactivation and mTORC1 hyperactivity.
Galectin-3 is a possible immunological target molecule of the pathogenic auto-antibodies
Mutational tuning of galectin-3 specificity and biological function.
The overall findings suggest that the secreted galectin-3 stimulated by PGF (show PGF Antibodies) plays a role in structural luteolysis by binding to beta 1 integrin.
The relative abundance of PIBF (show PIBF1 Antibodies), LGALS1 (show LGALS1 Antibodies), LGALS3 (show LGALS2 Antibodies), LGALS3BP (show LGALS3BP Antibodies), and LGALS9 (show LGALS9 Antibodies) mRNA would display a differential expression pattern in the endometrium.
Mycobacerium PtkA downregulates host Galectin 3, which is an anti-apoptotic molecule.
Antilymphoma activity by M(IFN-gamma (show IFNG Antibodies)/LPS (show TLR4 Antibodies)) macrophages was mediated, in part, by galectin-3. Intriguingly, aggressive lymphoma growth was markedly impaired in mice deficient in galectin-3, suggesting either that host galectin-3-mediated antilymphoma activity is required to sustain net tumor growth or that additional functions of galectin-3 drive key oncogenic mechanisms in non-Hodgkin's lymphoma.
galectin-3 is dynamically overexpressed in response to acute myocardial infarction-induced cardiac remodelling.
Lgals3, a PRC2 target gene encoding a multifunctional galactose-binding lectin, was derepressed in I363M heterozygotes, which enhanced the stemness of HSPCs. Thus, our work provides in vivo evidence that the structural integrity of EED (show EED Antibodies) to H3K27me3 propagation is critical, especially for embryonic development and hematopoietic homeostasis, and that its perturbation increases the predisposition to hematologic malignancies.
Increased galectin-3 levels are associated with abdominal aortic aneurysm progression. Galectin-3 inhibition with modified citrus pectin prevented AAA (show AAAS Antibodies) development.
Data suggest that different patterns of Pkd1 (show PKD1 Antibodies)-deficiency can lead to cardiac dysfunction and that galectin-3 has a role in intensifying this phenotype and limiting survival, effects potentially applicable to human autosomal dominant polycystic kidney disease.
This study reveals a uniquely regulated inflammatory response in the SVZ and shows that Gal-3 participates in remyelination in the cuprizone model.
Data demonstrated that the absence of host galectin-3 drastically affected the tumor biology favoring the metastatic spreading of 4T1 cells to inguinal lymph nodes and bone marrow colonization.
study demonstrated that endogenous Gal-3 is specifically involved in leukocyte slow rolling
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
35 kDa lectin
, beta-galactosides-binding lectin
, carbohydrate-binding protein 35
, galactose-specific lectin 3
, igE-binding protein
, laminin-binding protein
, lectin L-29
, lectin, galactoside-binding, soluble, 3 (galectin 3)
, mac-2 antigen
, 3 (galectin 3)
, CBP 35
, IgE-binding protein
, MAC-2 antigen
, lectin, galactoside-binding, soluble, 3
, galectin 3
, IgE binding protein
, lectin, galactose binding, soluble 3
, L-34 galactoside-binding lectin