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anti-Human Galectin 3 Antibodies:
anti-Rat (Rattus) Galectin 3 Antibodies:
anti-Mouse (Murine) Galectin 3 Antibodies:
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Human Polyclonal Galectin 3 Primary Antibody for CyTOF, FACS - ABIN4899436
Thijssen, Hulsmans, Griffioen: The galectin profile of the endothelium: altered expression and localization in activated and tumor endothelial cells. in The American journal of pathology 2008
Show all 5 Pubmed References
Human Monoclonal Galectin 3 Primary Antibody for IHC (f), ICS - ABIN2689513
Cherayil, Weiner, Pillai: The Mac-2 antigen is a galactose-specific lectin that binds IgE. in The Journal of experimental medicine 1990
Show all 4 Pubmed References
Human Polyclonal Galectin 3 Primary Antibody for IF (p), IHC (p) - ABIN672321
Lee, Bae, Choi, Park, Chun: Molecular cloning and expression analysis of pig CD7. in Veterinary research communications 2014
Show all 2 Pubmed References
Human Monoclonal Galectin 3 Primary Antibody for Func, IA - ABIN2192045
Liu, Hsu, Zuberi, Hill, Shenhav, Kuwabara, Chen: Modulation of functional properties of galectin-3 by monoclonal antibodies binding to the non-lectin domains. in Biochemistry 1996
Show all 3 Pubmed References
Human Monoclonal Galectin 3 Primary Antibody for ELISA, FACS - ABIN152697
Staels, Rubenstrunk, Noel, Rigou, Delataille, Millatt, Baron, Lucas, Tailleux, Hum, Ratziu, Cariou, Hanf: Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. in Hepatology (Baltimore, Md.) 2013
Show all 2 Pubmed References
Human Polyclonal Galectin 3 Primary Antibody for FACS - ABIN4896108
Richardson, Ludwinski, Gnanalingham, Atkinson, Freemont, Hoyland: Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration. in Scientific reports 2017
Mouse (Murine) Monoclonal Galectin 3 Primary Antibody for FACS - ABIN4896110
Ansa-Addo, Lange, Stratton, Antwi-Baffour, Cestari, Ramirez, McCrossan, Inal: Human plasma membrane-derived vesicles halt proliferation and induce differentiation of THP-1 acute monocytic leukemia cells. in Journal of immunology (Baltimore, Md. : 1950) 2010
Human Polyclonal Galectin 3 Primary Antibody for ELISA (Detection), FACS - ABIN4899434
Sioud, Mobergslien, Boudabous, Fløisand: Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins. in International journal of oncology 2010
Human Polyclonal Galectin 3 Primary Antibody for WB - ABIN517489
Shi, Tan, Meng, Yu, Li, Yin, Wei, Luo, Jia, Zhang, Wu, Mi, Wang: Association of anti-acidic ribosomal protein P0 and anti-galectin 3 antibodies with the development of skin lesions in systemic lupus erythematosus. in Arthritis & rheumatology (Hoboken, N.J.) 2014
Mouse (Murine) Monoclonal Galectin 3 Primary Antibody for EIA, FACS - ABIN114277
Knisley, Weitlauf: Compartmentalized reactivity of M3/38 (anti-Mac-2) and M3/84 (anti-Mac-3) in the uterus of pregnant mice. in Journal of reproduction and fertility 1993
Show all 12 Pubmed References
Demonstrate that galectin-3 plays a critical role in hensin (show DMBT1 Antibodies) ECM (show MMRN1 Antibodies) assembly by oligomerizing secreted monomeric hensin (show DMBT1 Antibodies).
this study reviews the role of galectin-3 in Atrial Fibrillation mechanisms and its potential therapeutic implications.
Our findings provide evidence that allele C of rs4652 and allele T of rs11125 in the galectin-3 gene may be risk factors for cervical cancer.
High GAL-3 expression is associated with Salivary Gland Tumor.
Galectin-3 is greatly reduced in patients with cutaneous lupus lesions compared with healthy controls, which may contribute to the recruitment of inflammatory cells in the skin.
Progesterone receptor (show PGR Antibodies), EGFR (show EGFR Antibodies), and galectin-3 are expressed differentially in uterine smooth muscle tumors.
Galectin-3 belongs to a class of inflammatory mediators that is associated with the degree of myocardial inflammation and fibrosis. It is related to the severity of myocardial ischemia and is negatively correlated with the cardiac ejection fraction.
Increased GAL-3 levels are an independent predictor of all-cause mortality in hemodialysis patients.
High GAL3 expression is associated with oral squamous cell carcinomas.
Studies indicate tumor-derived galectin-1 (show LGALS1 Antibodies), galectin-3 and galectin-9 (show LGALS9 Antibodies) in various cancers and anticancer therapies that target these molecules [Review].
High expression level of Galectin-3 and low expression level of TRAIL were found to be positively correlated with the shorter median survival time and overall survival time.
Mutational tuning of galectin-3 specificity and biological function.
The overall findings suggest that the secreted galectin-3 stimulated by PGF (show PGF Antibodies) plays a role in structural luteolysis by binding to beta 1 integrin.
The relative abundance of PIBF (show PIBF1 Antibodies), LGALS1 (show LGALS1 Antibodies), LGALS3 (show LGALS2 Antibodies), LGALS3BP (show LGALS3BP Antibodies), and LGALS9 (show LGALS9 Antibodies) mRNA would display a differential expression pattern in the endometrium.
Gal-3 and nSMase (show SMPD2 Antibodies), by inducing thyroid changes, might be the cause of the increased expression and altered distribution of TSH, thyroglobulin (show TG Antibodies), and TSHR (show TSHR Antibodies) or vice-versa.
Stroke (after left sided permanent middle cerebral artery occlusion) triggers central and peripheral galectin-3 release causing enteric neuronal loss through a TLR4 (show TLR4 Antibodies) mediated mechanism involving TAK1 (show NR2C2 Antibodies) and AMPK (show PRKAA1 Antibodies).
the secretion of galectin-3 as a novel mechanism for osteoblasts to control osteoclastogenesis and to maintain trabecular bone homeostasis independently of the RANKL/OPG (show TNFSF11 Antibodies)-axis.
Our findings establish gal-3 as a molecular regulator of the JAG1 (show JAG1 Antibodies)/Notch-1 (show NOTCH1 Antibodies) signaling pathway and have direct implications for the development of strategies aimed at controlling tumor angiogenesis.
Mycobacerium PtkA downregulates host Galectin 3, which is an anti-apoptotic molecule.
Antilymphoma activity by M(IFN-gamma (show IFNG Antibodies)/LPS (show TLR4 Antibodies)) macrophages was mediated, in part, by galectin-3. Intriguingly, aggressive lymphoma growth was markedly impaired in mice deficient in galectin-3, suggesting either that host galectin-3-mediated antilymphoma activity is required to sustain net tumor growth or that additional functions of galectin-3 drive key oncogenic mechanisms in non-Hodgkin's lymphoma.
galectin-3 is dynamically overexpressed in response to acute myocardial infarction-induced cardiac remodelling.
Lgals3, a PRC2 target gene encoding a multifunctional galactose-binding lectin, was derepressed in I363M heterozygotes, which enhanced the stemness of HSPCs. Thus, our work provides in vivo evidence that the structural integrity of EED (show EED Antibodies) to H3K27me3 propagation is critical, especially for embryonic development and hematopoietic homeostasis, and that its perturbation increases the predisposition to hematologic malignancies.
Increased galectin-3 levels are associated with abdominal aortic aneurysm progression. Galectin-3 inhibition with modified citrus pectin prevented AAA (show AAAS Antibodies) development.
Data suggest that different patterns of Pkd1 (show PKD1 Antibodies)-deficiency can lead to cardiac dysfunction and that galectin-3 has a role in intensifying this phenotype and limiting survival, effects potentially applicable to human autosomal dominant polycystic kidney disease.
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
35 kDa lectin
, beta-galactosides-binding lectin
, carbohydrate-binding protein 35
, galactose-specific lectin 3
, igE-binding protein
, laminin-binding protein
, lectin L-29
, lectin, galactoside-binding, soluble, 3 (galectin 3)
, mac-2 antigen
, 3 (galectin 3)
, CBP 35
, IgE-binding protein
, MAC-2 antigen
, lectin, galactoside-binding, soluble, 3
, galectin 3
, IgE binding protein
, lectin, galactose binding, soluble 3
, L-34 galactoside-binding lectin
, lectin, galactoside-binding, soluble, 2