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anti-Human Neurotrophin 3 Antibodies:
anti-Mouse (Murine) Neurotrophin 3 Antibodies:
anti-Rat (Rattus) Neurotrophin 3 Antibodies:
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Human Polyclonal Neurotrophin 3 Primary Antibody for IF (p), IHC (p) - ABIN725645
Guo, Cui, Peng, Fang, Zuo, Deng, Wang, Wu, Chen, Deng: Dietary NiCl₂ causes G₂/M cell cycle arrest in the broiler's kidney. in Oncotarget 2015
Cow (Bovine) Polyclonal Neurotrophin 3 Primary Antibody for ELISA - ABIN451691
Walz, Andreazza, Frey, Cacilhas, Ceresér, Cunha, Weyne, Stertz, Santin, Gonçalves, Kapczinski: Serum neurotrophin-3 is increased during manic and depressive episodes in bipolar disorder. in Neuroscience letters 2007
Human Monoclonal Neurotrophin 3 Primary Antibody for IHC, WB - ABIN2727202
Louie, Chen, Coomes, Ji, Tsirka, Chen: Neurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis. in Oncogene 2013
brain-derived neurotrophic factor (BDNF (show BDNF Antibodies)) and neurotrophin 3 (NT3) levels in post-mortem brain tissue from patients with depression compared to healthy individuals - a proof of concept study
NT-3 has been shown to be both an osteogenic and angiogenic factor (show VEGFA Antibodies), and can also enhance expression of the key osteogenic factor, BMP-2 (show BMP2 Antibodies), as well as the major angiogenic factor (show VEGFA Antibodies), VEGF (show VEGFA Antibodies), to promote bone formation, vascularization, and bone healing
High expression of NT-3 is associated with glioblastoma.
Meta-analysis found the levels of both NT-3 and NT-4/5 (show NTF4 Antibodies) were significantly increased in bipolar disorder patients. Through subgroup analysis, this increase persisted only in patients in depressed state, but not in manic or euthymic state. In addition, we found the differences in NT-3 and NT-4/5 (show NTF4 Antibodies) were significantly associated with the duration of illness, but not by the mean age or female proportion.
NT3 upregulates cellular proliferation, extracellular matrix protein production, and collagen deposition in human aortic valve interstitial cells through the Trk (show NTRK1 Antibodies)-Akt (show AKT1 Antibodies)-cyclin D1 (show CCND1 Antibodies) cascade.
The analysis of covariance (ANCOVA) indicated that the mean serum GDNF and NTF3 levels of ADHD patients were significantly higher than that of controls. However, serum BDNF (show BDNF Antibodies) and NGF (show NGFB Antibodies) levels did not show any significant differences between groups. These results suggest that elevated serum GDNF and NTF3 levels may be related to ADHD in children.
All patients had serum neurotrophin (show BDNF Antibodies) (NT-3, BDNF (show BDNF Antibodies), NGF (show NGFB Antibodies)) concentrations determined.
There were no differences in neurotrophin (show BDNF Antibodies) levels between patients with schizophrenia and controls. We found lower BDNF (show BDNF Antibodies) and higher NT-3 serum levels in depressed patients with schizophrenia.
The results suggest a gene dose-association between the A allele of rs6332 and the onset of AD in varepsilon4 non-carriers and the NTF-3 rs6489630 polymorphism being a relevant risk factor for AD in patients lacking the ApoE (show APOE Antibodies)-varepsilon4 allele in this Chinese sample.
Survival, differentiation, and neuroprotective mechanisms of human stem cells complexed with neurotrophin-3-releasing pharmacologically active microcarriers in an ex vivo model of Parkinson's disease.
By immunohistochemistry, the localization of Neurotrophinss has been observed mainly in Purkinje cells; TrkA (show NTRK1 Antibodies) and TrkB (show NTRK2 Antibodies)-receptors in cells and fibers of granular and molecular layers. TrkC (show NTRK3 Antibodies) was faintly detected
Deletion of a kinesin I motor unmasks a mechanism of homeostatic axon-branching control by neurotrophin-3.
studies for the first time have shown that NT-3 increases muscle fiber diameter in the neurogenic muscle through direct activation of mTOR (show FRAP1 Antibodies) pathway and that the fiber size increase is more prominent for fast twitch glycolytic fibers
that the NT3-TrkA (show NTRK1 Antibodies) complex uses Ras/MAPK (show MAPK1 Antibodies) and/or PI3K-AKT (show AKT1 Antibodies) signaling to induce axon growth and inhibit axon branching along intermediate targets
Here the authors demonstrate a novel function for p75(NTR (show NGFR Antibodies)) in regulating proper cell cycle exit of neuronal progenitors in the developing rat and mouse external granule layer, which is stimulated by proneurotrophin-3. In the absence of p75(NTR (show NGFR Antibodies)), cerebellar granule cell progenitors continue to proliferate beyond their normal period, resulting in a larger cerebellum that persists into adulthood, with consequent motor defici
NT-3-transduced bone marrow- derived neural stem cells differentiated into a greater number of cholinergic neurons.
Ntf3, but not Bdnf (show BDNF Antibodies), expression by postnatal supporting cells regulates cochlear function.
Study shows that dissociated cochlear nucleus neurons can be stimulated by neurotrophic factors BDNF (show BDNF Antibodies), NT-3, and FGF2 (show FGF2 Antibodies)
Data show that acteoside can up-regulate the expression of brain neurotrophin-3 (NT-3) in D-galactose combined with aluminum trichloride treated mice.
CAPS2 (show CADPS2 Antibodies) plays an important role in subcellular locality (axonal vs. somato (show SSTR5 Antibodies)-dendritic) of enhanced BDNF (show BDNF Antibodies) and NT-3 release, which is indispensable for proper development of postnatal cerebellum.
Uptake of NT-3 from irrigating vasculature and cerebrospinal fluid induces the rapid phosphorylation of endothelial nitric oxide
Loss of Ntf3, by contrast, causes an increase in layer VI neurons but does not rescue the Sip1 (show ZEB2 Antibodies) mutant phenotype, implying that other parallel pathways also control the timing of progenitor cell fate switch.
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
, nerve growth factor 2
, neurotrophic factor
, neurotrophin 3 - pending
, neurotrophin 3
, neurotrophin-3 (HDNF/NT-3)