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This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.
WAS protein family, member 2
, wiskott-Aldrich syndrome protein family member 2
, WASP family Verprolin-homologous protein 2
, WASP family protein member 2
, WASP family protein member 4
, protein WAVE-2
, putative Wiskott-Aldrich syndrome protein family member 4
, suppressor of cyclic-AMP receptor (WASP-family)
, verprolin homology domain-containing protein 2