anti-F-Box Protein 11 Antibodies

Protein Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with F-Box Protein 11 (FBXO11)

• F-box protein 11 (FBXO11) antibody
• F-box protein 11 (Fbxo11) antibody
• F-box protein 11 L homeolog (fbxo11.L) antibody
• F-box protein 11a (fbxo11a) antibody
• F-box only protein 11 (CpipJ_CPIJ009919) antibody
• Show all gene names
• F-box only protein 11 (CpipJ_CPIJ017549) antibody
• F-box only protein 11 (Bm1_52225) antibody
• hypothetical protein (LOAG_16571) antibody
• F-box protein 11 (fbxo11) antibody
• F-box protein 11 (LOC100115478) antibody

• C80048 antibody
• DKFZp459P2410 antibody
• FBX11 antibody
• Fbxo11 antibody
• im:6906507 antibody
• Show all synonym aliases
• Jf antibody
• MGC84634 antibody
• PRMT9 antibody
• UBR6 antibody
• Vit1 antibody
• wu:fj83f06 antibody
• zgc:153171 antibody

Protein level used designations for FBXO11

F-box only protein 11 , protein arginine N-methyltransferase 9 , ubiquitin protein ligase E3 component n-recognin 6 , vitiligo-associated protein 1 , vitiligo-associated protein VIT-1 , GENA 104 , jeff , F-box protein 11 , fj83f06 , F-box only protein 11-like , f-box only protein 11-like