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anti-Human EOMES Antibodies:
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Human Polyclonal EOMES Primary Antibody for WB - ABIN1881298
Wang, Ge, Xue, Li: [Role of transcription factor T-bet and Eomes in IFN-gamma secretion of different human T cell subsets]. in Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 2010
Show all 3 Pubmed References
Human Polyclonal EOMES Primary Antibody for IHC, IHC (p) - ABIN4308348
Mosenson, Zloza, Nieland, Garrett-Mayer, Eby, Huelsmann, Kumar, Denman, Lacek, Kohlhapp, Alamiri, Hughes, Bines, Kaufman, Overbeck, Mehrotra, Hernandez, Nishimura, Guevara-Patino, Le Poole: Mutant HSP70 reverses autoimmune depigmentation in vitiligo. in Science translational medicine 2013
Human Polyclonal EOMES Primary Antibody for CyTOF, FACS - ABIN4900371
Raab, Klingenstein, Möller, Illing, Tosic, Breunig, Kuales, Linta, Seufferlein, Arnold, Kleger, Liebau: Reprogramming to pluripotency does not require transition through a primitive streak-like state. in Scientific reports 2017
Human Monoclonal EOMES Primary Antibody for CyTOF, FACS - ABIN4900372
Latos, Sienerth, Murray, Senner, Muto, Ikawa, Oxley, Burge, Cox, Hemberger: Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks. in Genes & development 2015
Human Monoclonal EOMES Primary Antibody for FACS - ABIN4897601
Lunemann, Martrus, Goebels, Kautz, Langeneckert, Salzberger, Koch, J Bunders, Nashan, van Gisbergen, Altfeld: Hobit expression by a subset of human liver-resident CD56brightNatural Killer cells. in Scientific reports 2017
EOMES specifically activates a cardiogenic program in human embryonic stem cells.
Studies suggest there are two nonoverlapping NK cell populations that are potentially liver resident in humans: CD49a (show ITGA1 Antibodies)+ NK cells and Eomes hi.
Reciprocal regulation of BMF (show BMF Antibodies) and BIRC5 (show BIRC5 Antibodies) is linked to Eomes overexpression in colorectal cancer.
Eomes(hi) NK cells can be recruited from the circulation during adult life and that circulating Eomes(lo) NK cells are able to upregulate Eomes and molecules mediating liver retention under cytokine conditions similar to those in the liver.
EOMES expression was low in multiple sclerosis (MS), and stable over time. The low EOMES/TBX21 phenotype in MS reflects cd56 (show NCAM1 Antibodies)+ cell dysregulation.
we identified a higher Eomes mRNA expression as an independent good prognostic factor for OS and PFS in mRCC patients treated with sorafenib.
Eomes(+) CD4(+) T cells are increased in the peripheral blood and cerebrospinal fluid from patients in a progressive state of multiple sclerosis.
the level of T-bet and Eomesodermin, two T-box transcription factors regulating lymphocyte effector functions, is strongly reduced in NK cells from allogeneic hematopoietic stem cell transplantation recipients compared with healthy control subjects.
This study showed that EOMES (rs2724509; flanking) associated with Alzheimer disease.
This study supports the concept that poor human viral-specific CD8 (show CD8A Antibodies)(+) T cell functionality is due to an inverse expression balance between T-bet and Eomes
Smad2 (show SMAD2 Antibodies) and Eomesodermin a (Eomesa) bind common genomic regions proximal to genes involved in mesoderm and endoderm formation, suggesting Eomesa forms a general component of the Smad2 (show SMAD2 Antibodies) signalling complex in zebrafish.
Eomesa has a strictly maternal role in the initiation of epiboly, and is required for normal expression of the endoderm markers sox32, bon and og9x; however it is not essential for endoderm formation.
Eomes is a Nodal-transducing factor that acts, directly and indirectly, in concert with FoxH1 (show FOXH1 Antibodies) to carry out all Nodal-dependent processes during early mesendoderm specification.
Eomes plays a role in specifying the embryonic organizer.
regulates the expression of a zygotic homeobox (show PRRX1 Antibodies) transcription factor mtx2 (show MTX2 Antibodies)
Results suggest that eomesodermin promotes endoderm induction in marginal blastomeres by facilitating the assembly of a transcriptional activating complex on the casanova promoter.
These results suggest that both Eomes genes are involved in the zebrafish immune response, particularly in lymphocyte function as has been found in mammals.
as conceptuses attach to the uterine epithelium, IFNT gene transcription is down-regulated by an increase in EOMES expression and EOMES-CREBBP (show CREBBP Antibodies) binding in the attached trophoblast cells.
IL-12 (show IL12A Antibodies) promoted increasing T-bet and down regulating Eomes to promote the CD8 (show CD8A Antibodies)+ T cell differentiation to memory T-cells in invasive pulmonary aspergillosis mouse model.
These data indicate that TBR2 contributes to suppressing RA signaling in INPs, thereby enabling them to re-enter the cell cycle and delay neuronal differentiation.
These data identify TBR2 as a major determinant of the INP-specific traits by regulating both genetic and epigenetic pathways.
Tbr2 regulates the tempo of laminar fate implementation for all cortical layers.
results revealed Eomes expression is restricted to distinct tissues and Vgamma subsets; gammadelta T cells expressing Eomes presented a CD44 (show CD44 Antibodies)+-activated memory phenotype with increased expression of Ly6C and Il2rb (show IL2RB Antibodies) and showed higher IFN-gamma (show IFNG Antibodies) production upon stimulation; Eomes expression could be induced in peripheral and thymic gammadelta T cells by IL-12 (show IL12A Antibodies) and in particular by IL-4 (show IL4 Antibodies)
activation of the Eomes target genes Foxa2 (show FOXA2 Antibodies) and Lhx1 (show LHX1 Antibodies) is associated with higher order chromatin reorganization.
this study shows that TGF-beta (show TGFB1 Antibodies) promotes salivary gland innate lymphoid cells differentiation by suppressing Eomes
The Foxo3 (show FOXO3 Antibodies)-Eomes pathway is central to achieve the complete specialized gene program required for pathogenic Th1 (show HAND1 Antibodies) cell differentiation.
HDAC11-knockout T cells displayed enhanced proliferation, proinflammatory cytokine production, and effector molecule expression of Eomes and TBX21 transcription factors previously shown to regulate inflammatory cytokine and effector molecule production.
increases the number of ALP (show CCL21A Antibodies)-positive colonies after iPSC induction and decreases expression levels of Eomes and p21 (show D4S234E Antibodies) mRNAs. Based on these observations, we propose that the CCR4 (show CCR4 Antibodies)-NOT deadenylase activity contributes to iPSC induction.
the expression of T-bet, Eomes and GATA-3 (show GATA3 Antibodies) in combination with additional differentiation molecules within CD4 (show CD4 Antibodies)+ and CD8beta+ T cell subsets from different organs of healthy pigs.
This gene encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation.
T-box brain protein 2
, eomesodermin homolog
, eomesodermin homolog (Xenopus laevis)