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Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
RNA polymerase transcriptional regulation mediator-related
, mediator of RNA polymerase II transcription subunit 6
, mediator of RNA polymerase II transcription, subunit 6 homolog
, activator-recruited cofactor 33 kDa component
, renal carcinoma antigen NY-REN-28
, mediator complex subunit 6
, hypothetical protein