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AKR1C4 Antigen Profile
This gene encodes a member of the aldo\\/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and\\/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alternative names and synonyms associated with AKR1C4
aldo-keto reductase family 1 member C4 (AKR1C4) ELISA Kit
3-alpha-HSD ELISA Kit
C11 ELISA Kit
CDR ELISA Kit
CHDR ELISA Kit
DD-4 ELISA Kit
DD4 ELISA Kit
HAKRA ELISA Kit
Protein level used designations for AKR1C4
, aldo-keto reductase family 1 member C4
, chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4
, dihydrodiol dehydrogenase isozyme DD4
, type I 3-alpha-hydroxysteroid dehydrogenase