Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human CYP3A4 Antibodies:
anti-Mouse (Murine) CYP3A4 Antibodies:
anti-Rat (Rattus) CYP3A4 Antibodies:
Go to our pre-filtered search.
Human Polyclonal CYP3A4 Primary Antibody for IHC (p), WB - ABIN514838
Yamashita, Honda, Nio, Nakamoto, Yamashita, Takamura, Tani, Zen, Kaneko: Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation. in Cancer research 2010
Show all 3 Pubmed References
Human Polyclonal CYP3A4 Primary Antibody for Func, WB - ABIN2473177
Chirkov YuYu, Tyshchuk, Severina: Guanylate cyclase in human platelets with different aggregability. in Experientia 1990
Show all 3 Pubmed References
Human Monoclonal CYP3A4 Primary Antibody for ICC, FACS - ABIN969512
van Waterschoot, Rooswinkel, Sparidans, van Herwaarden, Beijnen, Schinkel: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. in Drug metabolism and disposition: the biological fate of chemicals 2009
Show all 2 Pubmed References
Human Polyclonal CYP3A4 Primary Antibody for WB - ABIN514839
De Bock, Colin, Boussery, Van Bocxlaer: Development and validation of an enzyme-linked immunosorbent assay for the quantification of cytochrome 3A4 in human liver microsomes. in Talanta 2012
Human Polyclonal CYP3A4 Primary Antibody for IP, WB - ABIN947776
Fujiwara, Itoh: Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome. in Pharmacology research & perspectives 2014
Human Polyclonal CYP3A4 Primary Antibody for ELISA - ABIN4302113
Choi, Skipper, Wishnok, Tannenbaum: Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450. in Drug metabolism and disposition: the biological fate of chemicals 2005
Cow (Bovine) Polyclonal CYP3A4 Primary Antibody for WB - ABIN2784528
Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. in Clinical pharmacology and therapeutics 2014
These results suggest that human and marmoset P450 (show CYP2B6 Antibodies) 3A4/90 and 4F12 in livers or small intestines played important roles in terfenadine t-butyl hydroxylation. Marmosets could be a model for humans during first pass extraction of terfenadine and related substrates.
This first description of CYP3A4*20 null genotype in liver-transplanted patients, supports the relevance of CYP3A genotyping in tacrolimus therapy
We demonstrate for the first time that the effect of ABCB1 (show ABCB1 Antibodies) diplotype on tacrolimus disposition is dependent on both CYP3A5 (show CYP3A5 Antibodies) and CYP3A4 genotype.
Some flavonoids exhibit selective inhibition toward CYP3A4 rather than other major cytochromes. Here, data suggest high risk of herb-drug interactions or food-drug interactions could be caused by flavonoids; vital structural elements of natural flavonoids could lead to interactions with clinical drugs normally eliminated via CYP3A4 metabolism.
Patients with CYP2C19 (show CYP2C19 Antibodies)*2 were at increased risk and CYP2C19 (show CYP2C19 Antibodies)*2, CYP3A5 (show CYP3A5 Antibodies)*3 and GSTP1 (show GSTP1 Antibodies) have synergistic influence on CYC (show CYCS Antibodies) failure.
The mAb concomitantly shifted IL-1beta (show IL1B Antibodies) IC50 values towards CYP3A4 activity.
CYP3A4 was identified as a novel tumor suppressor gene related to a poor prognosis in HCC (show FAM126A Antibodies).
In CYP3A4, the most energetically favorable docking mode places testosterone in a position with the methyl groups directed toward the heme iron
this study indicates that CYP3A activity is regained subsequent to kidney transplantation
Younger age, POR (show POR Antibodies)*28 allele, and CYP3A5 (show CYP3A5 Antibodies)*3 allele were associated with higher cyclosporine dosing requirements and lower concentration/dose ratio.
It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR Antibodies) and cytochrome b(5 (show CYB5A Antibodies)).
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
, P450-III, steroid inducible
, albendazole monooxygenase
, albendazole sulfoxidase
, cytochrome P450 3A3
, cytochrome P450 3A4
, cytochrome P450 HLp
, cytochrome P450 NF-25
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4
, cytochrome P450-PCN1
, glucocorticoid-inducible P450
, nifedipine oxidase
, quinine 3-monooxygenase
, taurochenodeoxycholate 6-alpha-hydroxylase
, cytochrome P450, family 3, subfamily A, polypeptide 4
, cytochrome P450 3A80
, Cytochrome P450 CM3A-10
, cytochrome P450 3A21
, cytochrome P450 CYP3A12