Browse our anti-Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) Antibodies

Zebrafish Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) interaction partners

1. c-mos (show MOS Antibodies) mRNA localizes with Zorba around the animal pole in the zebrafish oocyte suggesting that the animal cortex is the central core of oocyte maturation in zebrafish.

Human Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) interaction partners

1. Upon binding to p27(Kip1 (show CDKN1B Antibodies)) 3'UTR (show UTS2R Antibodies), CPEB1 promotes elongation of poly-A tail and the subsequent translation of p27(Kip1 (show CDKN1B Antibodies)) mRNA. This leads to higher levels of p27(Kip1 (show CDKN1B Antibodies)) in the cell, in turn significantly inhibiting cell proliferation, and confers to CPEB1 a potential value as a tumor suppressor in Glioblastoma.

2. CPEB1 regulation of MMP9 (show MMP9 Antibodies) mRNA expression mediates metastasis of breast cancer cells

3. The host RNA-binding protein (show PTBP1 Antibodies) CPEB1 was highly induced after cytomegalovirus infection and ectopic expression of CPEB1 in non-infected cells recapitulated infection-related post-transcriptional changes. CPEB1 was also required for poly(A)-tail lengthening of viral RNAs important for productive infection.

4. Expression levels of CPEB4 and CPEB1 genes are correlated with overall survival in patients with glioma.

5. WEE1 (show WEE1 Antibodies) is regulated at the translational level by CPEB1 and miR (show MLXIP Antibodies)-15b in a coordinated and cell-cycle-dependent manner.

6. This mechanical catalysis makes possible a positive feedback loop that would help localize the formation of CPEB fibers to active synapse areas and mark those synapses for forming a long-term memory after the prion form is established. The functional role of the CPEB helical oligomers in this mechanism carries with it implications for targeting such species in neurodegenerative diseases.

7. Structural Analysis of the Pin1 (show PIN1 Antibodies)-CPEB1 interaction and its potential role in CPEB1 degradation has been described.

8. Identify a mechanism of VEGF overexpression in liver and mesentery that promotes pathologic, but not physiologic, angiogenesis, via sequential and nonredundant functions of CPEB1 and CPEB4.

9. CPEB1, 2, and 4, are essential to successful mitotic cell division.

10. Results suggest that CPEB1-mediated translational control is essential for the differentiation of GSCs.

Mouse (Murine) Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) interaction partners

1. CPEB1 level was increased in the basolateral amygdala (BLA (show LACTB Antibodies)) of model mice injected with Complete Freund's Adjuvant. CPEB1 knockdown in the BLA (show LACTB Antibodies) can relieve anxiety-like behaviors but not pain-like behaviors by heightening inhibitory transmission and restoring the excitatory/inhibitory balance in model mice.

2. CPEB1 regulation of MMP9 (show MMP9 Antibodies) mRNA expression mediates metastasis of breast cancer cells

3. DAZL (show DAZL Antibodies) and CPEB1 regulate mRNA translation during oocyte maturation.

4. Identify a mechanism of VEGF overexpression in liver and mesentery that promotes pathologic, but not physiologic, angiogenesis, via sequential and nonredundant functions of CPEB1 and CPEB4.

5. cytoplasmic-element-binding control of transforming growth factor beta-activated kinase 1 (show MAP3K7 Antibodies) mRNA translation mediates the inflammatory immune response

6. Myoepithelial cells prevent EMT (show ITK Antibodies) by influencing the polarity and proliferation of luminal epithelial cells in a mechanism that requires translational silencing of myoepithelial Twist1 (show TWIST1 Antibodies) by CPEB1.

7. Fmr1 (show FMR1 Antibodies)(-/y); Cpeb1(-/-) double-knockout mice displayed amelioration of biochemical, morphological, electrophysiological and behavioral phenotypes associated with fragile X (show FMR1 Antibodies) syndrome.

8. poly(A) polymerase (show PAPOLA Antibodies) Gld2 (show PAPD4 Antibodies), deadenylase PARN (show PARN Antibodies), and translation inhibitory factor neuroguidin (Ngd (show NGDN Antibodies)) are components of a dendritic CPEB-associated polyadenylation apparatus

9. CPEB-mediated zonal occludens-1 mRNA localization is essential for tight-junction assembly and mammary epithelial cell polarity

10. when the Cpeb1 knockout mice were fed a high-fat diet, their livers became insulin (show INS Antibodies)-resistant.Our results show that Cpeb1 regulated translation is a key process involved in insulin (show INS Antibodies) signaling

Cow (Bovine) Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) interaction partners

1. CPEB, localized in oocyte cytoplasm, was hyperphosphorylated during prophase/metaphase-I transition.

Pig (Porcine) Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) interaction partners

1. Aurora kinase A (show AURKA Antibodies) is unlikely to be involved in CPEB1 activating phosphorylation and cyclin B1 (show CCNB1 Antibodies) mRNA polyadenylation during meiotic maturation of porcine oocytes.

2. results suggest the involvement of mammalian CPEB1 in Cyclin B syntheses and meiotic resumption in mammalian oocytes