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Human Monoclonal L1CAM Primary Antibody for IHC (fro), FACS - ABIN2689016
Lemmon, McLoon: The appearance of an L1-like molecule in the chick primary visual pathway. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1986
Show all 10 Pubmed References
Mouse (Murine) Monoclonal L1CAM Primary Antibody for CyTOF, FACS - ABIN4900808
He, Knepper, Ding, Li, Castro, Siddiqui, Schachner: Promotion of spinal cord regeneration by neural stem cell-secreted trimerized cell adhesion molecule L1. in PLoS ONE 2012
Human Monoclonal L1CAM Primary Antibody for FACS, IHC - ABIN4329609
Zhang, Wong, Wei, Gilkes, Korangath, Chaturvedi, Schito, Chen, Krishnamachary, Winnard, Raman, Zhen, Mitzner, Sukumar, Semenza: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs. in Oncogene 2012
Human Polyclonal L1CAM Primary Antibody for IHC, IHC (p) - ABIN4329611
Jørgensen, Bæk, Varming: Potentials and capabilities of the Extracellular Vesicle (EV) Array. in Journal of extracellular vesicles 2015
L1CAM promotes esophageal squamous cell carcinoma tumorigenicity by upregulating ezrin (show EZR Antibodies) expression.
TWIST1 (show TWIST1 Antibodies), in part via GAS6 (show GAS6 Antibodies) and L1CAM, led to higher expression and activation of Akt (show AKT1 Antibodies) upon cisplatin treatment, and inhibition of Akt (show AKT1 Antibodies) activation sensitized cells to cisplatin.
data make L1CAM a highly interesting therapeutic target to prevent further metastatic spread in melanoma patients
High circulating levels of autoantibodies against L1-cell adhesion molecule is associated with esophageal squamous cell carcinoma.
A functional role for L1CAM in extrahepatic cholangiocarcinoma carrying the activating KRAS mutation.L1CAM prmotes cell migration and invasion via JNK (show MAPK8 Antibodies) activation in extrahepatic cholangiocarcinoma.
this review and meta-analysis concludes that L1CAM might be an effective poor prognostic factor for patients with various tumor types
High L1CAM expression is associated with vulvar squamous cell carcinomas.
Our preclinical assessment of the CE7 epitope on CD171 supports its utility and safety as a CAR T-cell target for neuroblastoma (show ARHGEF16 Antibodies) immunotherapy
L1CAM may have a role in human endometrial cancer and miR (show MLXIP Antibodies)-34a has an inverse role to L1CAMEXP
L1CAM mRNA expression appears to play a substantial role in the pathophysiology of ovarian cancer that is translated into poor clinical outcome.
The present study provides evidence for a novel L1-mediated function of MBP (show MBP Antibodies) in the developing spinal cord and in the injured adult mammalian nervous system that leads to enhanced recovery after acute trauma.
induced expression of L1CAM or PSA (show NPEPPS Antibodies)-NCAM (show NCAM1 Antibodies) in the iPSC-derived DA neurons cannot completely restore the neurite outgrowth potential that was reduced in these DA neurons as a consequence of epigenetic aberrations resulting from the iPSC reprogramming process.
Heterozygous L1CAM-deficient mice express an autism-like phenotype.
tumors in stressed animals demonstrated markedly enhanced expression of VEGFR-2 (show KDR Antibodies) and L1CAM mRNA as well as pERK (show EIF2AK3 Antibodies), MMP-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies) protein expression.
Function-triggering antibodies to the adhesion molecule (show NCAM1 Antibodies) L1 enhance recovery after injury of the adult mouse femoral nerve.
We suggest that L1 stimulates neuritogenesis by activating CK2alpha leading to decreased levels of PTEN and p53 (show TP53 Antibodies) via a novel, L1-triggered and CK2alpha-mediated signal transduction pathway.
a positive relationship between L1 and pPKD1 in both cultured cerebellar neurons and human cerebellar tissue, suggesting that L1 functions in the modulation of PKD1 (show PKD1 Antibodies) phosphorylation.
Myelin basic protein (show MBP Antibodies) cleaves cell adhesion molecule (show MCAM Antibodies) L1 and promotes neuritogenesis and cell survival.
These results demonstrate that L1 promotes neuronal differentiation from ESCs (show NR2E3 Antibodies) through the L1-mediated enhancement of FUT9 (show FUT9 Antibodies) and ST3Gal4 (show ST3GAL4 Antibodies) expression.
L1 stimulation triggers sumoylation and cleavage of L1, thus generating the L1-70 fragment which is cleaved by cathepsin E (show CTSE Antibodies)
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
neural cell adhesion molecule L1
, antigen identified by monoclonal antibody R1
, N-CAM L1
, nerve-growth factor-inducible large external glycoprotein
, neuron-glia cell adhesion molecule (Ng-CAM)
, neuronal-glial cell adhesion molecule