Browse our anti-CD247 (CD247) Antibodies

Full name:: anti-CD247 Molecule Antibodies (CD247)

On www.antibodies-online.com are 294 CD247 Molecule (CD247) Antibodies from 26 different suppliers available. Additionally we are shipping CD247 Proteins (13) and CD247 Kits (4) and many more products for this protein. A total of 324 CD247 products are currently listed.

Synonyms:: 4930549J05Rik, A430104F18Rik, AW552088, Cd3, Cd3-eta, CD3-ZETA, CD3H, CD3Q, Cd3z, Cd3zeta, CD247, im:7156386, LOC100136514, LOC100136549, LOC100305023, T3Z, Tcrk, TCRZ, TCRzeta

list all antibodies	Gene Name	GeneID	UniProt
	CD247	12503	P29020 , P24161
	CD247	919	P20963
	CD247	25300
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Most Popular Reactivities for anti-CD247 (CD247) Antibodies

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anti-Mouse (Murine) CD247 Antibodies:

anti-Human CD247 Antibodies:

anti-Rat (Rattus) CD247 Antibodies:

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Top referenced anti-CD247 Antibodies

Mouse (Murine) Monoclonal CD247 Primary Antibody for CyTOF, FACS - ABIN4900709 : Jones, Stumhofer, Foster, Twohig, Hertzog, Topley, Williams, Hunter, Jenkins, Wang, Jones: Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 (PubMed)
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Mouse (Murine) Monoclonal CD247 Primary Antibody for CyTOF, FACS - ABIN4900710 : Kipnis, Cardon, Avidan, Lewitus, Mordechay, Rolls, Shani, Schwartz: Dopamine, through the extracellular signal-regulated kinase pathway, downregulates CD4+CD25+ regulatory T-cell activity: implications for neurodegeneration. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
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Mouse (Murine) Monoclonal CD247 Primary Antibody for CyTOF, FACS - ABIN4900705 : Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac. in The Biochemical journal 2013 (PubMed)
Show all 7 Pubmed References
Mouse (Murine) Monoclonal CD247 Primary Antibody for CyTOF, FACS - ABIN4900706 : Fan, Zhang, Huang, Liu, Guo, Zhang, Luo: Optimizations of siRNA design for the activation of gene transcription by targeting the TATA-box motif. in PLoS ONE 2014 (PubMed)
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Human Monoclonal CD247 Primary Antibody for WB - ABIN967618 : Alberola-Ila, Takaki, Kerner, Perlmutter: Differential signaling by lymphocyte antigen receptors. in Annual review of immunology 1997 (PubMed)
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Human Monoclonal CD247 Primary Antibody for FACS, IF - ABIN965779 : Dumont, Blanchard, Di Bartolo, Lezot, Dufour, Jauliac, Hivroz: TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
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Human Monoclonal CD247 Primary Antibody for IP, WB - ABIN967517 : Hall, Sancho, Terhorst: Reconstitution of T cell receptor zeta-mediated calcium mobilization in nonlymphoid cells. in Science (New York, N.Y.) 1993 (PubMed)
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Human Monoclonal CD247 Primary Antibody for ICC, FACS - ABIN1724734 : Nambiar, Fisher, Warke, Krishnan, Mitchell, Delaney, Tsokos: Reconstitution of deficient T cell receptor zeta chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus. in Arthritis and rheumatism 2003 (PubMed)
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Mouse (Murine) Monoclonal CD247 Primary Antibody for FACS - ABIN4898316 : Lin, Xu, Jin, Zhong, Di, Lin: CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice. in Fertility and sterility 2009 (PubMed)
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Mouse (Murine) Monoclonal CD247 Primary Antibody for FACS - ABIN4898315 : Ghareeb, Elwakeel, Khalil, Aziz, El Demellawy: Investigation of the Immunomodulatory effect of Berberis vulgaris on core-pulsed dendritic cell vaccine. in BMC complementary and alternative medicine 2016 (PubMed)
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More Antibodies against CD247 Interaction Partners

Zebrafish CD247 Molecule (CD247) interaction partners

The structure of the adaptor protein cd3zeta has been identified in the zebrafish genome.

Mouse (Murine) CD247 Molecule (CD247) interaction partners

ITAM sequence diversity is required for optimal TCR signal transduction and subsequent T cell maturation
Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 (show CCR7 Antibodies) and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice
There is an early (within seconds) interaction between CD3zeta and the coreceptor CD8 that is independent of the binding of CD8 to MHC.
The resting TCR localized in the disordered domain of giant plasma membrane (PM) vesicles (GPMVs) and PM spheres (PMSs) and single and nanoclustered TCRs are found in the high-density fractions in sucrose gradients.
When Ly108 (show SLAMF6 Antibodies) is engaged in trans during cell-cell interactions, Ly108 (show SLAMF6 Antibodies)-CD3zeta interactions are promoted in a manner that uniquely depends on Ly108 (show SLAMF6 Antibodies) TM domain, leading to more efficient CD3zeta dephosphorylation.
Two transcription factor binding sites and a long non-coding RNA are identified within the Cd247 gene.
Zfat (show ZFAT Antibodies)-deficiency results in a loss of CD3zeta phosphorylation with dysregulation of ERK (show EPHB2 Antibodies) and Egr (show EGR1 Antibodies) activities leading to impaired positive selection.
The results of this study supported the model that the procognitive function of CD3zeta may be mediated through its involvement in the NMDAR (show GRIN1 Antibodies) downstream signaling pathway leading to CaMKII (show CAMK2G Antibodies)-dependent LTP (show SCP2 Antibodies) induction.
T cell CD3zeta deficiency enables multiorgan tissue inflammation.
Tyrosine phosphorylation of the TCR-zeta cytoplasmic domain regulates its association with the plasma membrane

Human CD247 Molecule (CD247) interaction partners

Long-term lung function decline in asthma is associated with elevation of bronchial CD8 and CD4 at baseline, and CD8, CD3 and granzyme B at follow-up
Crk-dependent increased phosphorylation of CD3zeta coincided with inhibition of TCR downmodulation, supporting a positive role for Crk adaptor proteins in TCR-mediated signal amplification.
the immunohistochemical staining patterns of CD3 (show CD3 Antibodies) and CD20 (show MS4A1 Antibodies) in Malignant Lymphoma Cells, were investigated.
CD274 (show CD274 Antibodies) up-regulation in new-onset type 1 diabetes mellitusis correlated with disease pathogenesis.
our observations suggested that CD247 gene polymorphism (rs858554) may associated with the susceptibility of RA.
CD3 (show CD3 Antibodies)/28-activated T cells expanded in IL-7 (show IL7 Antibodies) and IL-15 (show IL15 Antibodies) produced greater expansion of memory stem T cells and central memory T cell-derived T cells compared with IL-2 (show IL2 Antibodies). Our strategy provides a powerful tool to elucidate the characteristics of CAR-modified T cells, regardless of the protocol used for expansion, reveals the functional properties of each expanded T cell subset.
Multiple mutations were found in CD247 complementary DNAs (cDNAs) cloned from the patient as well as in cDNA and genomic DNA from other individuals, suggesting that genetic variation in this gene is frequent.
Single-nucleotide polymorphism in CD247 gene is associated with sclerotic graft-versus-host disease.
CD3Z hypermethylation was significantly correlated with SLE. CD3Z hypermethylation is an SLE risk factor that can be modified by environmental factors and is associated with more severe SLE clinical manifestations, which are related to deranged T cell function by downregulating the CD3zeta-chain.
Linkage and association studies revealed a chromosomal region in which a novel type 1 diabetes (T1D)/autoimmune thyroid disease (AITD) susceptibility gene, CD247, is located and showed association between T1D/AITD and several variants in this gene. These results suggests that common susceptibility genes act in concert with variants of CD247 to generate genetic risk for T1D/AITD in this population.

Pig (Porcine) CD247 Molecule (CD247) interaction partners

CD247 Antigen Profile

Antigen Summary

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with CD247

CD247 antigen like (cd247l) antibody
CD3zeta-2 (cd3z) antibody
CD3zeta-1 (cd3z) antibody
CD247 molecule (cd247) antibody
CD247 molecule (CD247) antibody
CD247 antigen (Cd247) antibody
Cd247 molecule (Cd247) antibody

4930549J05Rik antibody
A430104F18Rik antibody
AW552088 antibody
Cd3 antibody
Cd3-eta antibody
CD3-ZETA antibody
CD3H antibody
CD3Q antibody
Cd3z antibody
Cd3zeta antibody
CD247 antibody
im:7156386 antibody
LOC100136514 antibody
LOC100136549 antibody
LOC100305023 antibody
T3Z antibody
Tcrk antibody
TCRZ antibody
TCRzeta antibody

Protein level used designations for anti-CD247 Molecule (CD247) Antibodies

, , , , , , , , , , , , , , , , , , , , , , , CD247 antigen like cd3zetal CD3zeta-like CD247 antigen-like CD3zeta-2 T-cell surface glycoprotein CD3 zeta chain CD3zeta-1 CD3 zeta CD247 molecule cd3zeta CD3 antigen, zeta polypeptide CD3-zeta/eta T-cell receptor T3 eta chain CD247 antigen, zeta subunit CD3Z antigen, zeta polypeptide (TiT3 complex) CD3zeta chain T-cell antigen receptor complex, zeta subunit of CD3 T-cell receptor T3 zeta chain TCR zeta chain CD247 antigen T-cell receptor CD3 subunit zeta T-cell receptor CD3, subunit zeta CD3 zeta chain CD3 Zeta chain

GENE ID	SPECIES
100101465	Danio rerio
100136514	Salmo salar
100136549	Salmo salar
100305023	Ictalurus punctatus
748272	Pan troglodytes
100101654	Danio rerio
12503	Mus musculus
919	Homo sapiens
25300	Rattus norvegicus
397302	Sus scrofa
100008617	Oryctolagus cuniculus
443436	Ovis aries

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Show all anti-CD247 Molecule (CD247) Antibodies with Pubmed References