anti-Human ACD antibody for Western Blotting

Recommended ACD Antibody (supplied by: Log in to see )

Antigen
Adrenocortical Dysplasia Homolog (Mouse) (ACD) Antibodies
  • PIP1
  • PTOP
  • TINT1
  • TPP1
  • ACD
  • ACD, shelterin complex subunit and telomerase recruitment factor
  • adrenocortical dysplasia
  • ACD
  • Acd
Epitope
C-Term
11
6
4
4
2
2
2
2
1
1
1
1
1
Reactivity
Human
76
28
23
4
4
4
4
1
Host
Rabbit
53
23
7
Clonality
Polyclonal
Conjugate
This ACD antibody is un-conjugated
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
65
24
15
13
13
9
8
7
4
2
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Catalog No. ABIN2787610
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.08196 ABIN2787609 WB Rabbit Middle Region Log in to see Polyclonal 0
3.08196 ABIN2779815 WB Rabbit C-Term Log in to see Polyclonal 0
3.08196 ABIN395038 ELISA IF IHC IP WB Mouse IgG1 kappa AA 1-545 Log in to see S1 5
3.08196 ABIN2715649 FACS IF WB Mouse IgG1 Log in to see 1A2 0
3.08196 ABIN2715647 IF WB Mouse IgG2b Log in to see 1C8 0
3.08196 ABIN442140 IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal 0
3.08196 ABIN1326997 IP ELISA WB Mouse IgG1 kappa AA 1-544, full length Log in to see 1C11-1A7 0
3.08196 ABIN4890167 WB Rabbit Log in to see Polyclonal 0
3.08196 ABIN949606 IP WB Rabbit AA 1-544, full length Log in to see Polyclonal 0
3.08196 ABIN528772 ELISA WB Mouse IgG1 kappa AA 1-544, full length Log in to see 1C11-1A7 0
3.08196 ABIN631477 WB Rabbit Log in to see Polyclonal 0
3.08196 ABIN631593 WB Rabbit Log in to see Polyclonal 0
3.08196 ABIN4277586 IHC WB Mouse IgG1 Log in to see 2B1 0
3.08196 ABIN5997183 WB Rabbit IgG Log in to see Polyclonal 0
3.08196 ABIN528770 WB Mouse AA 1-544, full length Log in to see Polyclonal 0
3.08196 ABIN528771 WB Rabbit AA 1-544, full length Log in to see Polyclonal 0
3.08196 ABIN4277584 FACS ICC IF WB Mouse IgG1 Log in to see 1A-2 0
1 ABIN1496406 IHC IHC (p) WB Mouse IgG1 Log in to see 2B1 0
1 ABIN322241 WB Rabbit IgG AA 398-447 Log in to see Polyclonal 0
1 ABIN477902 WB Rabbit IgG AA 467-516 Log in to see Polyclonal 0

General

Antigen Adrenocortical Dysplasia Homolog (Mouse) (ACD) Antibodies
Epitope C-Term
(11), (6), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(76), (28), (23), (4), (4), (4), (4), (1)
Host Rabbit
(53), (23), (7)
Clonality
Polyclonal
Conjugate This ACD antibody is un-conjugated
(3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(65), (24), (15), (13), (13), (9), (8), (7), (4), (2)
Pubmed 1 reference available
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Product Details anti-ACD Antibody

Target Details ACD Application Details Handling References for anti-ACD antibody (ABIN2787610) Images
Blocking Peptide Blocking peptide for this product available: ABIN972808
Sequence SSQPSPAICS APATLTPRSP HASRTPSSPL QSCTPSLSPR SHVPSPHQAL
Predicted Reactivity Human: 100%
Characteristics This is a rabbit polyclonal antibody against ACD. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ACD
Plasmids, Primers & others

Target Details ACD

Product Details anti-ACD Antibody Application Details Handling References for anti-ACD antibody (ABIN2787610) Images back to top
Antigen
Alternative Name ACD (ACD Antibody Abstract)
Background ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
Alias Symbols: PIP1, PTOP, TINT1, TPP1
Protein Interaction Partner: TINF2, ANXA8L1, POT1, USP7, CUL5, ZNF790, PAGE2, APOBEC3F, NUDCD2, LRRC25, TRIM15, AFAP1L2, TBC1D10A, PDLIM2, RBKS, ANKMY2, PGM2, SBDS, LGALSL, DBNL, AIPL1, NCDN, STIP1, TOMM34, NUDC, TRIM16, TUBB4B, STUB1, FAM131B, BAG3, RECQL4, EIF3G, FKBP6, YWHAE, TUBB
Protein Size: 544
Molecular Weight 58 kDa
Gene ID 65057
NCBI Accession NM_001082486, NP_001075955
UniProt Q96AP0
Pathways Telomere Maintenance

Application Details

Product Details anti-ACD Antibody Target Details ACD Handling References for anti-ACD antibody (ABIN2787610) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 544 AA

Restrictions For Research Use only

Handling

Product Details anti-ACD Antibody Target Details ACD Application Details References for anti-ACD antibody (ABIN2787610) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACD antibody (ABIN2787610)

Product Details anti-ACD Antibody Target Details ACD Application Details Handling Images back to top
Background publications

Hockemeyer, Palm, Else, Daniels, Takai, Ye, Keegan, de Lange, Hammer: "Telomere protection by mammalian Pot1 requires interaction with Tpp1." in: Nature structural & molecular biology, Vol. 14, Issue 8, pp. 754-61, 2007

Images

Product Details anti-ACD Antibody Target Details ACD Application Details Handling References for anti-ACD antibody (ABIN2787610) back to top
Supplier Images
Western Blotting (WB) image for anti-Adrenocortical Dysplasia Homolog (Mouse) (ACD) (C-Term) antibody (ABIN2787610) WB Suggested Anti-ACD Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1...