Browse our RFC4 Proteins (RFC4)

Full name:: Replication Factor C (Activator 1) 4, 37kDa Proteins (RFC4)

On www.antibodies-online.com are 14 Replication Factor C (Activator 1) 4, 37kDa (RFC4) Proteins from 6 different suppliers available. Additionally we are shipping RFC4 Antibodies (62) and and many more products for this protein. A total of 82 RFC4 products are currently listed.

Synonyms:: 21.m03053, 44.t00003, A1, AI894123, AU040575, rfc2, rfc4, RFC37

list all proteins	Gene Name	GeneID	UniProt
	RFC4	106344	Q99J62
Rat RFC4	RFC4	288003
	RFC4	5984	P35249
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Human Replication Factor C (Activator 1) 4, 37kDa (RFC4) interaction partners

Expression level of RFC4 was up regulated in cervical squamous cell carcinoma.
RFC4 is frequently overexpressed in CRC (show CALR Proteins), and is associated with tumor progression and worse survival outcome. This might be attributed to the regulation of CRC (show CALR Proteins) cell proliferation and cell cycle arrest by RFC4
The knockdown of endogenous replication factor C4 decreases the growth and enhances the chemosensitivity of hepatocellular carcinoma cells.

RFC4 Protein Profile

Protein Summary

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

Alternative names and synonyms associated with RFC4

replication factor C subunit 4 (PFL2005w)
Replication factor C subunit 4 (EHI_167150)
replication factor C subunit 4 (TP03_0432)
replication factor C subunit 4 (Tb11.01.1310)
replication factor C subunit 4 (BBOV_IV002210)
replication factor C subunit 4 (rfc4)
Replication factor C subunit 4 (rfc-4)
replication factor C (activator 1) 4 (Rfc4)
replication factor C subunit 4 (Rfc4)
replication factor C subunit 4 (RFC4)
replication factor C subunit 4 L homeolog (rfc4.L)

21.m03053 protein
44.t00003 protein
A1 protein
AI894123 protein
AU040575 protein
rfc2 protein
rfc4 protein
RFC37 protein

Protein level used designations for RFC4

replication factor C subunit 4 , Replication factor C subunit 4 , activator 1 subunit 4 , A1 37 kDa subunit , RF-C 37 kDa subunit , RFC 37 kDa subunit , activator 1 37 kDa subunit , replication factor C 37 kDa subunit , replication factor C p37 subunit , replication factor C 4

GENE ID	SPECIES
811453	Plasmodium falciparum 3D7
3409096	Entamoeba histolytica HM-1:IMSS
3500242	Theileria parva strain Muguga
3664295	Trypanosoma brucei brucei strain 927/4 GUTat10.1
5477605	Babesia bovis T2Bo
100195740	Salmo salar
175976	Caenorhabditis elegans
106344	Mus musculus
288003	Rattus norvegicus
5984	Homo sapiens
398706	Xenopus laevis
478667	Canis lupus familiaris
504637	Bos taurus

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