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Our study demonstrated that ATP1B3 inhibit EV71 replication by enhancing the production of type-I interferons, which could act as a potential therapeutic target in EV71 infection.
Data suggest that ATP1B3 is binding partner of BST-2 and regulates stability of BST-2; ATP1B3 is co-factor that accelerates BST-2 degradation and reduces BST-2-mediated restriction of HIV-1 replication/tropism and NFkappaB activation.
B7H3 (show CD276 Proteins) and ATP1B3 are overexpressed in tumor endothelial cells, favoring an angiogenic phenotype.
role in T and B lymphocyte (show AKAP17A Proteins) activation
These results evidenced that the beta3 subunit of Na, K ATPase (show ATP1A1 Proteins) is (show ATP11A Proteins) expressed on RBC (show CACNA1C Proteins) membrane but the epitope recognized by mAb P-3E10 is hidden in normal RBCs (show SSU1 Proteins). we showed the association of beta3 subunit and alpha subunit (show POLG Proteins) of Na, K ATPase (show ATP1A1 Proteins).
Elevated Na+ -K+ -ATPase (show ATP1A1 Proteins) activity postexercise may contribute to reduced fatigue after training.
These findings indicate that the beta3 subunit of the Na+,K+-ATPase (show ATP1A1 Proteins) is (show ATP11A Proteins) a novel determinant of nociceptive sensitivity and further supports the notion that pain variability genes have selective effects on individual pain modalities.(ATP1BETA3, MOUSE)
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
Na, K-ATPase beta-3 polypeptide
, sodium pump subunit beta-3
, sodium-potassium ATPase subunit beta 3 (non-catalytic)
, sodium/potassium-dependent ATPase beta-3 subunit
, sodium/potassium-dependent ATPase subunit beta-3
, sodium/potassium-transporting ATPase beta-3 chain
, sodium/potassium-transporting ATPase subunit beta-3
, ATPase, Na+K+ transporting, beta polypeptide 3
, Na+/K+ -ATPase beta 3 subunit
, (Na+,K+)-ATPase-beta-2 subunit
, Na+,K+-ATPase beta-3 subunit
, Na+/K+ ATPase beta 3 subunit
, ATPase, Na+/K+ beta 3 polypeptide
, Na K-ATPase beta-3 subunit